Question
Attaching a single unit of this protein to P.C.N.A induces translesion synthesis, while adding further copies of this protein in a chain promotes the template-switching pathway. Loss of E.6-A.P, which attaches this protein, causes Angelman syndrome. Like many enzymes that recognise this protein, the V.H.L protein contains a RING finger domain. During S-phase, cyclins D and E are modified with this protein by the S.C.F complex. Chains of this protein are most commonly (*) K48- or K63-linked. Attaching this protein to a substrate via one of its 7 lysine residues involves a cascade of activation, conjugation, and ligation steps catalysed by namesake E1, E2 and E3 enzymes. Unlike the related SUMO proteins, this protein is used to tag proteins destined for proteasomal degradation. For 10 points, which small protein is named for its presence in nearly all cells? ■END■
Buzzes
Player | Team | Opponent | Buzz Position | Value |
---|---|---|---|---|
Sharath Narayan | Palestrina Sawayama | Weird Klaus Barbie | 51 | 15 |
Ethan Ashbrook | Jeff Weiner Fan Club | doubleplusnegfive | 103 | 10 |
Shardul Rao | Our Job is Buzz | BHSU | 134 | 10 |