When this drug is infused too quickly, it activates the MRGPRX2 receptor to cause its namesake flushing reaction, which presents as a rash on the face, neck, and upper torso. For 10 points each:
[10h] Name this glycopeptide antibiotic that inhibits cell wall synthesis. Resistance to this antibiotic in Enterococcus and S. aureus is mediated by alterations to peptidoglycan’s D-alanyl-D-alanine motif.
ANSWER: vancomycin
[10e] Vancomycin is most commonly administered via this route, which may use a PICC (“pick”) line. Drugs administered via this route have 100% bioavailability due to being infused directly into the bloodstream.
ANSWER: IV [or intravenous; prompt on parenteral]
[10m] Oral vancomycin treats infections caused by a member of this genus which proliferates in the gut following broad-spectrum antibiotic treatment. Renshaw Cells are targeted by a toxin produced by a member of this genus.
ANSWER: Clostridium [accept Clostridiodies; accept Clostridium or Clostridiodies difficile; accept Clostridium tetani; prompt on C. difficile or C.tetani]
<EG, Biology>