A 2004 article about this application highlights the unrecoverable alterations of clone identifiers and changes to gene names like “Deleted in Esophageal Cancer 1.” For 10 points each:
[10m] Name this application, a successor to ones like Lotus 1-2-3. A 2016 Genome Biology article found that roughly 1/5th of supplementary gene lists contain incorrect gene names due to this software package.
ANSWER: Microsoft Excel (The gene DEC1 is converted to 1-DEC, as in the date.)
[10h] A 2021 article in this publisher’s Computational Biology shows that gene name errors have continued. This open-access publisher with a multidisciplinary “ONE” journal was co-founded by Patrick Brown and Michael Eisen.
ANSWER: PLOS (“plaws”) [or Public Library of Science; accept PLOS ONE]
[10e] Opening data in Excel truncated off records for almost 16,000 cases of this disease in 2020, which complicated test-and-trace protocols.
ANSWER: COVID-19 [or SARS-CoV-2 or coronavirus]
<EK, Current Events>