An A31P mutation in the cardiac myosin binding protein C gene is responsible for hypertrophic cardiomyopathy, the most common heart disease affecting these non-human animals. For 10 points each:
[10m] Name these animals that, along with ferrets, are common [emphasize] atypical hosts of Dirofilaria immitis. CSD caused by Bartonella henselae is spread through the saliva of these animals, which carry the only parasitic TORCH disease.
ANSWER: cats (Dirofilaria is heartworm; CSD is Cat Scratch Disease; T in Torch is Toxoplasmosis.)
[10e] Hypertrophic cardiomyopathy in cats is characterized by the abnormal thickness of the left ventricle, which obstructs blood flow into this largest artery in the body.
ANSWER: aorta
[10h] Cats suffering from hypertrophic cardiomyopathy can be treated with the antithrombotic clopidogrel, which inhibits this ADP receptor. Aspirin and this receptor’s inhibitor are used during dual antiplatelet therapy following coronary stenting.
ANSWER: P2Y12 [prompt on P2Y]
<AY, Biology>