In bacteria, these molecules can form OLE (“O-L-E”) structures implicated in stress-response. The bridge helix of a protein that synthesizes this molecule can be inhibited by alpha-amanitin. These molecules can form a hammerhead structure originally discovered in tobacco ringspot virus that has catalytic activity. This molecule can form the PPT that interacts with the spliceosome, which also contains small nuclear examples of these molecules. A hypothesis named for this molecule’s world posits that its ability to self-replicate predates the existence of other biomolecules. This molecule with non-coding and transfer subtypes pairs adenine with uracil. For 10 points, name this usually single-stranded biomolecule that can be prefixed “m” for messenger. ■END■
ANSWER: RNA [or ribonucleic acid; accept RNA world or RNA synthase or snRNAs or ncRNAs or tRNAs or mRNAs]
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