These molecules are protonated by water, preventing the formation of a magnesium intermediate. For 10 points each:
[10m] What molecules are normally dissolved in nonpolar solvents like diethyl ether and contain both magnesium and a halogen? These species attach R groups to carbonyls through alkoxide intermediates.
ANSWER: Grignard reagents [or Grignard compounds]
[10h] Grignards are sometimes dissolved in this organic solvent that consists of a five-membered ring containing an oxygen. This solvent’s ether group strongly complexes to magnesium and it is also used in hydroboration reactions.
ANSWER: THF [or tetrahydrofuran; accept oxolane or 1,4-epoxybutane or 1-oxacyclopentane]
[10e] Water cannot be used in Grignard reactions as the reagents are strong examples of these hydrogen-accepting molecules. These molecules contrasted with acids also include sodium hydroxide.
ANSWER: bases [accept basic molecules; accept strong bases; accept Brønsted–Lowry bases; accept Lewis bases]
<Editors, Chemistry>