They’re not amyloids, but production of ester derivatives of this molecule can be inhibited by CP-113818. SQS converts two molecules of FPP to a key intermediate in the synthesis of this molecule. The INSIG protein lowers production of this molecule by binding to a domain of SCAP, preventing migration of this molecule to the Golgi apparatus. Linear isoprene units are a precursor to this cyclized molecule through a squalene intermediate. Macrophage-like foam cells contain a form of this molecule called LDL, which can be inhibited by statins. High levels of this molecule can lead to fatty plaque deposits in the walls of arteries. For 10 points, what molecule maintains membrane fluidity and is a lipid implicated in heart disease? ■END■
ANSWER: cholesterol [prompt on lipids until read]
<Editors, Biology>
= Average correct buzz position