TNF family receptors may trigger the extrinsic form of this process upon viral infection, which viruses may deliberately induce to assist viral particle spread. For 10 points each:
[10e] Name this orderly process of programmed cell death often contrasted with necrosis.
ANSWER: apoptosis
[10m] The E1B 19K protein of adenoviruses blocks mechanisms of apoptosis both dependent and independent of this protein. Normally, this protein arrests the cell cycle at the G1/S (“G-one-S”) checkpoint in response to DNA damage.
ANSWER: p53 [or TP53; or tumor protein 53]
[10h] Viruses engage in the apoptotic form of this phenomenon by expressing phosphatidylserine (“phospha-tidyl-serine”) on their envelope. The immune system attacks the proteolipid protein of myelin after mistaking it as hepatitis B protein in this phenomenon’s “molecular” form.
ANSWER: mimicry [accept apoptotic mimicry; accept molecular mimicry; or word forms like mimic]
<GC, Biology>