Wistar-Kyoto rats were originally designed for studies related to hypertension, but are now often used as an animal analogue of this condition. For 10 points each:
[10e] Name this condition of persistent low mood, which often includes anhedonia (“an-hee-DOE-nee-uh”).
ANSWER: depression [or major depressive disorder; or MDD; accept equivalents like being depressed; prompt on melancholy or melancholia by asking “what is the modern equivalent?”]
[10h] One indication that Wistar-Kyoto rats are typically depressed is that they record fewer activities in this test. In this test, often used to examine antidepressants, rats are placed in a container from which they cannot escape.
ANSWER: forced swim test [or forced swimming test; or Porsolt forced swimming test; or behavioral despair test]
[10m] Wistar-Kyoto rats more easily enter this condition, which Martin Seligman linked with depression. Seligman demonstrated this behavior by finding that dogs that could not escape initial shocks did not escape from later shocks.
ANSWER: learned helplessness [or LH]
<Benjamin McAvoy-Bickford, Social Science>