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One of these molecules is chemically linked to a cytotoxic payload in an ADC, a form of targeted cancer therapy. HAT medium is used to incubate hybridomas in a technique for producing large amounts of one type of these molecules. These molecules’ hinge regions connect their Fab (“F-A-B”) and Fc (“F-C”) regions. The diversity of certain receptors and these molecules is facilitated through V(D)J recombination. A type of these proteins that only recognizes a single target is called “monoclonal.” These proteins can class-switch between their five isotypes and consist of two heavy chains and two light chains. For 10 points, B cells produce what Y-shaped proteins that bind to antigens? ■END■
| Upstate NY | Main | Y | 5 | 100% | 0% | 0% | 83.20 |
| Southern California | Main | Y | 7 | 86% | 0% | 14% | 61.67 |
| Eastern Canada (1) | Main | Y | 5 | 100% | 0% | 0% | 68.60 |
| Eastern Canada (2) | Main | Y | 9 | 89% | 0% | 11% | 69.75 |
| Florida | Main | Y | 1 | 100% | 0% | 0% | 94.00 |
| Great Lakes | Main | Y | 12 | 100% | 0% | 33% | 79.00 |
| Lower Mid-Atlantic | Main | Y | 9 | 89% | 0% | 11% | 66.38 |
| Upper Mid-Atlantic | Main | Y | 12 | 100% | 0% | 8% | 71.75 |
| Midwest | Main | Y | 9 | 100% | 0% | 0% | 68.22 |
| North | Main | Y | 1 | 100% | 0% | 0% | 80.00 |
| Northeast | Main | Y | 12 | 92% | 0% | 8% | 81.73 |
| Pacific | Main | Y | 9 | 100% | 0% | 11% | 81.00 |
| South Central | Main | Y | 4 | 100% | 0% | 0% | 70.75 |
| Southeast | Main | Y | 13 | 100% | 0% | 15% | 94.00 |
| Northern California | Main | Y | 1 | 100% | 0% | 100% | 94.00 |
| UK (South) | UK | Y | 8 | 100% | 0% | 0% | 59.00 |
| UK (North) | UK | Y | 5 | 100% | 0% | 0% | 87.20 |
| Player | Team | Opponent | Buzz Position | Value |
|---|---|---|---|---|
| Sarah Dong | Michigan A | Michigan State A | 39 | 10 |
| Anna Liao | Michigan B | CWRU B | 46 | 10 |
| Sai Subramanian | CWRU A | Louisville A | 48 | 10 |
| Arjun Saulnier | CWRU C | Kentucky | 57 | -5 |
| Pratham Bhanushali | WVU B | Louisville C | 62 | 10 |
| Joseph Strom | Louisville B | CWRU D | 62 | 10 |
| Jacob Goodson | Ohio State A | Ohio State B | 73 | -5 |
| Bonham Buchannon | Louisville D | Pittsburgh | 75 | -5 |
| Reed Sexton | Michigan C | Michigan State B | 76 | 10 |
| Nishad Joshi | Kentucky | CWRU C | 79 | 10 |
| Eric Cameron | Michigan State C | Michigan State D | 100 | -5 |
| Agatha Dahle | WVU A | Ohio State D | 104 | 10 |
| Andrew McKenzie | Ohio State B | Ohio State A | 108 | 10 |
| Jack Rabaut | Michigan D | Ohio State C | 108 | 10 |
| Zac Stapler | Pittsburgh | Louisville D | 108 | 10 |
| Elena Yarrington | Michigan State D | Michigan State C | 108 | 10 |