strokes - 2024 PLAYTIME @ Harvard

Question

Recent studies have been testing biomarkers of oxidative stress such as xanthine oxidase, glutathione, and MMP-9 to predict the risk of one of these events. For 10 points each:

[10e] Name these events identified with the mnemonic BE·FAST. These events with “ischemic” and “hemorrhagic” types are caused by blockage of blood flow to the brain or the bursting of a blood vessel in the brain.

ANSWER: strokes [or cerebrovascular accidents or CVAs; accept ischemic strokes; accept hemorrhagic strokes; accept brain attacks]

[10h] A type of these enzymes called tissue plasminogen activator can be injected to break up blood clots to treat ischemic strokes. Proteins in the serpin superfamily are named for being “inhibitors” of these enzymes.

ANSWER: serine proteases [or serine proteinases or serine endopeptidases; prompt on proteases or endopeptidases]

[10m] The International Stroke Trial discovered a U-shaped relationship between death or dependency from stroke and this quantity. ACE inhibitors lower levels of angiotensin II, which in turn lowers this quantity.

ANSWER: blood pressure [or BP; prompt on sodium levels with “what other quantity is lowered with low levels of angiotensin II?”]

<SM, Biology>

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Summary


2025 PLAYTIME @ CWRU	12/10/2024	Y	5	18.00	80%	100%	0%
2025 PLAYTIME @ Claremont	12/10/2024	Y	5	18.00	100%	80%	0%
2025 PLAYTIME @ Florida	12/10/2024	Y	3	16.67	67%	100%	0%
2024 PLAYTIME @ Harvard	04/26/2025	Y	4	7.50	50%	25%	0%
2024 PLAYTIME @ JHU	10/26/2024	Y	4	17.50	100%	75%	0%
2025 PLAYTIME @ Northwest	12/10/2024	Y	4	12.50	50%	75%	0%
2025 PLAYTIME Online	04/26/2025	Y	9	18.89	89%	89%	11%
2025 PLAYTIME @ Sheffield	12/10/2024	Y	7	18.57	86%	100%	0%
2024 PLAYTIME @ UBC	10/05/2024	Y	8	17.50	63%	100%	13%
2024 PLAYTIME @ Virginia Tech	07/11/2025	Y	3	20.00	100%	100%	0%
2024 PLAYTIME @ WashU	10/12/2024	Y	6	20.00	83%	100%	17%