Question
After migration from this structure, transit-amplifying cells begin to differentiate into one of four cell types. For 10 points each:
[10h] Name these populations of intestinal stem cells. LGR5+ cells located at these pitted structures can also differentiate in +4 cells and Paneth cells.
ANSWER: intestinal crypts [or colonic crypts; accept crypts of Lieberkühn; prompt on intestinal glands; prompt on stem-cell niches]
[10m] Some transit-amplifying cells will mature into this cell type responsible for lubricating the villus epithelium. Most of the mucin (“MEW-sin”) found in the human body is produced by these cells.
ANSWER: goblet cells
[10e] Transit-amplifying cells can also differentiate into cells called enterocytes (“en-tair-roe-SITES”) that facilitate this molecule’s uptake using a sodium cotransporter. This molecule is converted into pyruvate during glycolysis.
ANSWER: glucose [accept sodium-glucose transporter; prompt on sugars or saccharides; prompt on carbohydrates]
<Kane Nguyen, Biology>
Summary
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