Question

The viability and tolerability of this drug were confirmed during the PIONEER and SUSTAIN clinical trial programs. Like another similar short-lasting medication developed by Lotte Bjerre Knudsen, this drug possesses a spacer that links a lysine residue to a C18 fatty di-acid. A position 2 substitution from alanine to 2-amino⋅iso⋅butyric acid prevents this drug from being degraded by dipeptidyl peptidase-4. This drug, which is an (*) incretin mimetic and is sold under the name Rybelsus (10[1])by Novo Nordisk, reduces blood sugar levels in adults with type 2 diabetes. (10[2])In 2023, (-5[1])this drug accounted for over 88% of all GLP-1s being prescribed. (10[1])For 10 points, semaglutide is the generic name of what drug that has recently seen widespread use as a weight-loss medication? ■END■

ANSWER: Ozempic [or Wegovy; accept Rybelsus until “Rybelsus” is read; accept semaglutide until “semaglutide” is read; prompt on GLP-1 receptor agonist or glucagon-like peptide-1 receptor agonist until “GLP-1s” is read]
<Benjamin McAvoy-Bickford, Biology>
= Average correct buzz position

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Buzzes

PlayerTeamOpponentBuzz PositionValue
Aseem KeyalbruhWe jopping7310
Tomás Aguilar-FragaStatler and Waldorfesque Former Penn Bowl EditorsKhalil v Carbolic Shisha Ball Co8610
Ashwath SeetharamanWhy the Kremlin Hates BananasTOAD8610
Ashish SubramanianOh you like geography? Name every Forrest.Ill-Advised Buzz88-5
Eric MukherjeeIll-Advised BuzzOh you like geography? Name every Forrest.9910

Summary

2024 Penn Bowl Playtest10/12/2024Y4100%0%25%86.00