Question
“Pathogen-associated” and “damage-associated” classes of these motifs are the primary ligands for toll-like receptors. For 10 points each:
[10m] Name this class of motifs on molecules like flagellin and lipopolysaccharide which provoke an innate immune response upon receptor binding. Toll-like receptors belong to a class of “recognition receptors” for these motifs.
ANSWER: molecular patterns [accept pattern recognition receptors; accept PAMPs and DAMPs]
[10e] Damage-associated molecular patterns are released from cells upon damage induced by a pathogen. One DAMP is this molecule, which, when found outside of the nucleus and mitochondria, binds to TLR9.
ANSWER: DNA [or deoxyribonucleic acid]
[10h] Cytosolic DNA is recognized by proteins in a pathway that is named for a cyclic dinucleotide synthase and a protein that mediates type-I interferon production. Name either of those two proteins.
ANSWER: cGAS-STING pathway [accept either underlined portion]
<Omer, Biology>
Summary
| 2024 ESPN @ Stanford | 03/09/2024 | Y | 2 | 10.00 | 50% | 50% | 0% |
Data
| Berkeley A | Stanford | 10 | 0 | 0 | 10 |
| Free Agents | Berkeley B | 0 | 10 | 0 | 10 |