Question
Researchers at this institution pioneered the use of cancer avatars, organisms implanted with human tumors on which chemotherapeutics may be tested. For 10 points each:
[10h] Name this institution that runs the Mouse Genome Informatics database. This institution is the source for thousands of the strains of transgenic mice used in labs worldwide.
ANSWER: Jackson Laboratory [accept JAX]
[10m] Much of the Jackson Laboratory’s collection of transgenic mice were bred using a recombination system based on this recombinase. In that system, this phage P1-derived recombinase is controlled by a doxycycline-activated promoter and mediates site-specific recombination at target-sites.
ANSWER: Cre recombinase [accept the cre-lox system or cre-lox recombination]
[10e] The transgenic mice the Jackson Laboratory creates are usually derived from the C57BL/6 strain of inbred mice, which is unusually sensitive to this stimulus. This stimulus is sensed by nociceptors.
ANSWER: pain [prompt on nociception]
<Omer, Biology>
Summary
| 2024 ESPN @ Chicago | 03/23/2024 | Y | 6 | 13.33 | 83% | 33% | 17% |
| 2024 ESPN @ Columbia | 03/23/2024 | Y | 7 | 18.57 | 100% | 86% | 0% |
| 2024 ESPN @ Duke | 03/23/2024 | Y | 2 | 15.00 | 100% | 50% | 0% |
Data
| Oh the Missouri | >:3 | 0 | 10 | 10 | 20 |
| Michigan | malcolm in the middlemarch (Purdue 1) | 0 | 0 | 10 | 10 |
| 2 days into college and I'm 3 lectures behind | purdoobie brothers | 0 | 0 | 0 | 0 |
| Chicago A Minus Minus | Charlotte Mewing to get that chiseled farmer’s bride jawline | 10 | 10 | 10 | 30 |
| Chicago B | BHSU | 0 | 0 | 10 | 10 |
| Noli Me Tangerine | Nobodaddy but you | 0 | 0 | 10 | 10 |