Question
Researchers at this institution pioneered the use of cancer avatars, organisms implanted with human tumors on which chemotherapeutics may be tested. For 10 points each:
[10h] Name this institution that runs the Mouse Genome Informatics database. This institution is the source for thousands of the strains of transgenic mice used in labs worldwide.
ANSWER: Jackson Laboratory [accept JAX]
[10m] Much of the Jackson Laboratory’s collection of transgenic mice were bred using a recombination system based on this recombinase. In that system, this phage P1-derived recombinase is controlled by a doxycycline-activated promoter and mediates site-specific recombination at target-sites.
ANSWER: Cre recombinase [accept the cre-lox system or cre-lox recombination]
[10e] The transgenic mice that the Jackson Laboratory creates are usually derived from the C57BL/6 strain of inbred mice, which is unusually sensitive to this stimulus. This stimulus is sensed by nociceptors.
ANSWER: pain [prompt on nociception]
<Omer, Biology>
Summary
| 2024 ESPN @ Brown | 04/06/2024 | Y | 3 | 20.00 | 100% | 100% | 0% |
| 2024 ESPN @ Cambridge | 04/06/2024 | Y | 2 | 15.00 | 100% | 50% | 0% |
| 2024 ESPN @ Online | 06/01/2024 | Y | 3 | 23.33 | 100% | 67% | 67% |
Data
| Jason Lovers | Clark A | 0 | 10 | 10 | 20 |
| Jeffrey and Dahmers | Clark B | 0 | 10 | 10 | 20 |
| Triple Round Robin Lovers | Labour's Lost Lovers | 0 | 10 | 10 | 20 |