Question
The paper that put forth this model also defines different types of the “domain of bonding” as “homologous” or “isologous” associations. For 10 points each:
[10h] Name this model opposed by the KNF or “sequential” model. It states that all subunits are regulated together to be favored towards a “tense” or “relaxed” state.
ANSWER: concerted model [or MWC model or Monod–Wyman–Changeux model; accept symmetry model]
[10m] This molecule, which is formed in the Luebering–Rapoport pathway, is the second-highest-concentrated metabolite in erythrocytes after glucose. In a classic example of negative allosteric regulation, the binding of this molecule stabilizes the tense state of hemoglobin, lowering its affinity for oxygen.
ANSWER: 2,3-BPG [or 2,3-bisphosphoglyceric acid or 2,3-bisphosphoglycerate; accept 2,3-DPG or 2,3-diphosphoglyceric acid or 2,3-diphosphoglycerate]
[10e] In another example of allosteric regulation, this enzyme is inhibited by ATP and its product G6P. This enzyme phosphorylates glucose in the first step of glycolysis.
ANSWER: hexokinase
<KP, Chemistry>
Summary
| 2024 Chicago Open | 07/28/2024 | Y | 1 | 30.00 | 100% | 100% | 100% |
Data
| LMM's LLM MLM | BHSU B | 10 | 10 | 10 | 30 |