Question

During cell fate conversion, condensed facultative heterochromatin is opened up by the “pioneer” subset of these proteins. For 10 points each:
[10m] Name these proteins whose “general” subset forms a preinitiation complex that binds to a TATA box. These proteins regulate the recruitment of RNA polymerase and thus the synthesis of mRNA.
ANSWER: transcription factors [or TFs; prompt on pioneer factors]
[10e] Transcription factors often recruit chromatin remodelers to modify these proteins. DNA wraps around an octamer of these proteins to form a nucleosome.
ANSWER: histones
[10h] These molecules bind to transcription factors and prevent DNA binding during decoying. 200 nucleotides are the minimum length of these molecules that are synthesized by RNA polymerase II and not used for translation.
ANSWER: long non-coding RNA [or lncRNA; prompt on non-coding RNA or ncRNA; prompt on RNA]
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Summary

2024 Booster Shot (Columbia)02/23/2024Y61.6717%0%0%
2024 Booster Shot (Great Lakes)03/09/2024Y615.00100%50%0%
2024 Booster Shot (Vanderbilt)03/02/2024Y412.5075%50%0%
2024 Booster Shot (WUSTL)03/09/2024Y20.000%0%0%
2024 Booster Shot (Waterloo)02/23/2024Y410.0075%25%0%

Data

Columbia ALehigh B0000
GathererBard0000
Lehigh ANYU C0000
NYU AColumbia B0000
NYU BPrinceton0000
YaleRutgers010010