Question

In 2020, Amy Wood et. al. created a molecular probe derived from these molecules’ KLVFFAE region. The p24 family protein TMP21 regulates the production of these molecules. The Arctic mutation decreases levels of these molecules, in contrast to the higher levels found as a result of the Swedish mutation. The thioflavin Pittsburgh compound B is often used in PET scans to image these molecules. A form of angiopathy named for these molecules is often indicated by (*) congo red staining. Inheriting the epsilon-4 allele of the ApoE gene can lead to lower degradation of these (-5[1])molecules. Beta- (-5[1])and gamma-secretases form these molecules by cleaving APP. Large deposits of these molecules characterize (-5[1])a certain disease, along with the presence of neurofibrillary tangles. (-5[1])For 10 points, name these peptides whose deposits create namesake “plaques” characteristic (10[1])of Alzheimer’s disease. ■END■ (10[1]0[2])

ANSWER: amyloid beta [or A-Beta; accept amyloid beta or beta-amyloid plaques; prompt on amyloid]
<Science - Biology>
= Average correct buzz position

Back to tossups

Buzzes

PlayerTeamOpponentBuzz PositionValue
Adrian WongThe Only Existing Manuscript from A Clockwork Orangeas rational as the square root of two power bottoms93-5
Tony ChenSimpson Agonistes: The Crisis of DonutTensei Shitara Flashcard Data Ken95-5
Sheena LiCommunism is Soviet power plus the yassification of the whole countryRyan Wesley Routh's 10 000 NATO-trained Afghan Quizbowlers109-5
Liam KusalikYou cannot go to Aarhus to see his peat-brown head / With eyes like ripening fruitShe Dicer On My Argonaute Till I RNA Interfere119-5
Kane NguyenI'd prefer to have the team name be Christensen et al. than anything that Erik cooks upModerator Can't Neg me While in Alpha13110
Caleb OttTensei Shitara Flashcard Data KenSimpson Agonistes: The Crisis of Donut1350
Jason ZhangShe Dicer On My Argonaute Till I RNA InterfereYou cannot go to Aarhus to see his peat-brown head / With eyes like ripening fruit13510
Jack van NostrandRyan Wesley Routh's 10 000 NATO-trained Afghan QuizbowlersCommunism is Soviet power plus the yassification of the whole country1350

Summary

2024 ARGOS @ McMaster11/17/2024Y540%0%80%133.00