Question
Mutations in the gene that codes for protein 4.1 can cause elliptocytosis because protein 4.1 links this protein to actin. For 10 points each:
[10h] Name this protein whose alpha and beta types combine to form tetramers that bind to actin filaments. Pentagons or hexagons of those tetramers made of this protein are the basis of the cytoskeletal network.
ANSWER: spectrin [accept alpha-spectrin or beta-spectrin]
[10e] Spectrin is so named because it was the main component of the leftover "ghosts" of these cells when Marchesi and Steersand lysed them. A protein found in these cells is a tetramer of heme groups.
ANSWER: red blood cells [or erythrocytes]
[10m] Many traumatic brain injuries cause spectrin to be cleaved by calpain, which leads to this process. A pro-inflammatory cytokine is named for its ability to induce this process in tumors.
ANSWER: necrosis [accept necroptosis; accept tumor necrosis factor alpha; prompt on premature cell death; prompt on TNF-alpha]
<Science - Biology>
Summary
| 2024 ARGOS @ Chicago | 11/23/2024 | Y | 1 | 30.00 | 100% | 100% | 100% |
Data
| BHSU Rebirth | BHSU ReFantazio | 10 | 10 | 10 | 30 |