Question
The Sicilian gambit was a tabular alternative to the Vaughan Williams scheme for a class of drugs targeting this organ. For 10 points each:
[10m] Name this organ whose workload is managed by ACE (“ace”) inhibitors. Venomous toads in the genus Bufo and poisonous plants in the genus Digitalis produce steroid glycosides named for targeting this organ.
ANSWER: heart [prompt on cardiac glycosides]
[10e] Cardiac glycosides treat arrhythmias by inhibiting the ATPase that pumps this ion against sodium.
ANSWER: potassium [or K-plus; accept sodium–potassium pump or sodium–potassium ATPase]
[10h] This form of V-tach can be triggered by dozens of drugs that have the human Ether-a-go-go-related gene as an antitarget. QT prolongation is a risk factor for this arrhythmia, in which premature beats twist peaks below the isoelectric line.
ANSWER: torsade de pointes (“tor-SOD duh pwant”) [or TdP; prompt on ventricular tachycardia]
<Biology>
Summary
| 2024 ACF Nationals | 2024-04-21 | Y | 21 | 15.71 | 100% | 38% | 19% |
Data
| Chicago D | Waterloo | 0 | 10 | 0 | 10 |
| Claremont Colleges | Chicago C | 0 | 10 | 0 | 10 |
| McGill | Columbia A | 0 | 10 | 0 | 10 |
| North Carolina B | Columbia B | 10 | 10 | 10 | 30 |
| Cornell A | Michigan | 0 | 10 | 0 | 10 |
| Duke | Chicago B | 0 | 10 | 0 | 10 |
| Georgia Tech | Arizona State | 0 | 10 | 0 | 10 |
| NYU | Harvard | 10 | 10 | 0 | 20 |
| Toronto A | Indiana | 10 | 10 | 10 | 30 |
| Iowa State | Florida | 0 | 10 | 0 | 10 |
| Brown | Minnesota A | 0 | 10 | 0 | 10 |
| North Carolina A | Berkeley B | 10 | 10 | 0 | 20 |
| Truman State | Northwestern | 0 | 10 | 0 | 10 |
| Purdue | Maryland | 0 | 10 | 0 | 10 |
| Texas | South Carolina | 10 | 10 | 10 | 30 |
| Berkeley A | Toronto B | 10 | 10 | 0 | 20 |
| Virginia | Kentucky | 10 | 10 | 0 | 20 |
| Johns Hopkins | WUSTL A | 0 | 10 | 10 | 20 |
| Chicago A | WUSTL B | 0 | 10 | 0 | 10 |
| Cornell B | Yale A | 10 | 10 | 0 | 20 |
| Yale B | Stanford | 0 | 10 | 0 | 10 |