Question

A covalently-bound retinal molecule undergoes an 11-cis to all-trans isomerisation when this protein absorbs light. For 10 points each:
[10m] Name this G-protein-coupled receptor that mediates vision in dim light.
ANSWER: rhodopsin [accept visual purple; do NOT accept ‘channelrhodopsin’]
[10e] Thousands of rhodopsin molecules are found in each outer segment disc in these photoreceptor cells, which are distributed toward the outer edges of the retina and are responsible for night vision, unlike cones.
ANSWER: rods [or rod cells]
[10h] Zemelman and Miesenböck pioneered the use of rhodopsin in this neuromodulation technique.
ANSWER: optogenetics

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2023 UMN COOT08/19/2023Y320.00100%100%0%

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