Question

The Archaean nrdJ gene encodes a “Class II” type of one of these enzymes that uses deoxy·adenosyl·cobalamin to activate a cysteine residue. In the presence of one of its four regulatory molecules, one of these enzymes clamps down its ten-stranded beta/alpha barrel to bring together the active and specificity sites. ADA deficiency inhibits DNA synthesis since a buildup of dATP inhibits one of these enzymes that uses two ferric iron atoms to generate a stable tyrosyl (tie-roh-SEEL) free radical. One of these enzymes uses (*) NADPH to convert gluta·thione from its inactive di·sulfide form to its active sulf·hydryl form. Enzymes of this type convert (-5[1])di·hydro·folate to tetra·hydro·folate, convert ribo·nucleotides to (10[1])de·oxy·ribo·nucleotides, and convert HMG-CoA to a cholesterol precursor. For 10 points, what kind of enzyme adds electrons to its substrate? (10[2])■END■

ANSWER: reductases [accept ribonucleotide reductase, glutathione reductase, dihydrofolate reductase, or HMG-CoA reductase; prompt on oxidoreductases or deoxygenases]
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= Average correct buzz position

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Buzzes

PlayerTeamOpponentBuzz PositionValue
Martin ProfantParth et al.Neg 5! Playing Quizbowl, Liddy Style102-5
Tony ChenThe Passion According to C.H.Milan et al.10810
Colin VeeversNeg 5! Playing Quizbowl, Liddy StyleParth et al.12810
Liam KusalikThe Vulture's Guide to BuzzCameron et al.12810

Summary

2023 BHSU @ Northwestern02/25/2023Y6100%0%33%118.17
2023 BHSU @ Maryland03/11/2023Y367%0%33%105.00
2023 BHSU @ Berkeley03/18/2023Y3100%0%33%115.33
2023 BHSU @ Yale04/08/2023Y3100%67%33%80.00
2023 BHSU @ Yale04/08/2023Y3100%33%33%109.67
2023 BHSU @ Yale04/08/2023Y3100%0%0%75.00
2023 BHSU Online04/15/2023Y4100%25%25%102.00
2023 BHSU @ Sheffield04/15/2023Y250%0%0%122.00
2023 BHSU @ Waterloo04/15/2023Y3100%0%33%121.33