Question
This reaction superseded the Castro–Stephens reaction by removing the need for copper as a catalyst for the cross-coupling step. For 10 points each:
[10h] Name this cross-coupling reaction used to couple aryl or vinyl halides to alkynes.
ANSWER: Sonogashira cross-coupling
[10m] The Sonogashira coupling is catalyzed by copper and this incredibly expensive metal, which also catalyzes the Heck, Stille, and Suzuki couplings.
ANSWER: palladium [or Pd]
[10e] The catalytic cycle for palladium cycles between its oxidation state of this number and its plus-two state. This is the charge of a neutral atom.
ANSWER: zero [accept +0]
<Chemistry>
Summary
| 2023 ACF Winter @ Columbia | 11/11/2023 | Y | 6 | 13.33 | 100% | 33% | 0% |
Data
| Columbia A | NYU A | 0 | 0 | 10 | 10 |
| Columbia B | Yale A | 0 | 0 | 10 | 10 |
| Cornell C | Rutgers A | 0 | 10 | 10 | 20 |
| Yale B | Haverford | 0 | 0 | 10 | 10 |
| Penn A | Princeton A | 0 | 10 | 10 | 20 |
| Princeton B | NYU B | 0 | 0 | 10 | 10 |