Question
Answer the following about anandamide, a molecule named for the Sanskrit word for “bliss.” For 10 points each:
[10e] Anandamide was the first endogenously discovered example of a class of molecules named for this plant. THC mediates the psychoactive effects of this plant by binding to CB1 and CB2 receptors in the brain.
ANSWER: cannabis [accept obvious equivalents such as marijuana or weed or pot; accept Cannabis sativa or Cannabis indica or Cannabis ruderalis]
[10m] CB1 receptors are part of this class of proteins, which have seven transmembrane helices and can act as guanine nucleotide exchange factors when bound by a ligand like anandamide.
ANSWER: G-protein coupled receptors [or GPCRs; accept serpentine receptors or metabotropic receptors or heptahelical receptors or G-protein linked receptors or GPLRs; reject “G-proteins”]
[10h] Anandamide is metabolized into this molecule, which is oxidized further to produce most eicosanoids. Aspirin blocks the conversion of this molecule into inflammatory prostaglandins by inhibiting cyclooxygenase enzymes.
ANSWER: arachidonic acid [prompt on AA or ARA]
<Biology>
Summary
| 2023 ACF Winter @ Columbia | 11/11/2023 | Y | 7 | 15.71 | 100% | 43% | 14% |