insulin - 2025 ACF Winter - Buzzpoints App

Question

An enzyme that primarily degrades this protein forces substrates to refold into beta-sheets in a triangular prism-shaped active site. Two disulfide bonds stabilize the two chains of this protein, (10[1]-5[2])which originate from cleavage (10[1])of a single precursor that assembles (10[1])into (10[1])hexameric (10[2]-5[1])complexes (10[2])that coordinate to zinc. (10[1])This protein propagates (10[1])signals after binding a receptor tyrosine (10[1])kinase that triggers the PI3K (10[1]-5[1])and ERK (10[2])pathways. Intracellular vesicles (-5[1])sensitive to this protein express the protein GLUT4. (10[2])Amylin (10[5]-5[1])and this hormone (10[2])are (10[1])produced in the islets (-5[1])of (10[1])Langerhans (10[8])in beta (10[2])cells (10[3])of (10[1])the (10[3])pancreas. (10[2])This hormone (10[1])promotes (10[2])the formation (10[2])of glycogen. (10[4]-5[1])For (10[2])10 (10[1])points, name this peptide (10[1])hormone that promotes (-5[1])absorption (-5[1])of glucose (10[1])that is deficient (0[1])in diabetes. (10[1])■END■ (10[10])

ANSWER: insulin

= Average correct buzz position

Summary


2025 ACF Nationals	2025-08-09	Y	9	100%	0%	0%	78.11
Canada	Main	Y	6	100%	0%	0%	85.00
Florida	Main	Y	12	100%	0%	33%	85.75
Great Lakes	Main	Y	3	100%	0%	0%	89.00
Overflow	Main	Y	1	100%	0%	0%	41.00
California	Main	Y	4	100%	0%	25%	80.00
South Central	Main	Y	5	100%	0%	0%	91.40
UK	Main	Y	4	75%	0%	25%	90.33
Upper Mid-Atlantic	Main	Y	8	100%	0%	25%	85.75
Upstate NY	Main	Y	8	100%	0%	0%	76.50
Pacific Northwest	Main	Y	10	100%	0%	20%	77.40

Buzzes

Player	Team	Opponent	Buzz Position	Value
Abby Smith	Berkeley B	Stanford A	28	-5
Michael Xu	McMaster C	Toronto C	28	10
Russell Nip	British Columbia D	Washington A	28	-5
Yusuf Baig	McMaster A	Carleton	32	10
Joel Dicker	Southampton A	Oxford A	38	10
Tianyu Xu	Georgia Tech A	Georgia Tech B	39	10
Aatreyo Bhattacharyya	Berkeley C	Stanford B	40	10
Thomas Brittain	McMaster B	Guelph A	40	-5
Bryan Ugaz	Arizona State A	McGill D	40	10
Braxton Davis	Missouri A	WashU A	41	10
Samarth Ram	Chicago B	Purdue C	41	10
Shiva Tegulla	UCF A	UCF B	45	10
Jakub Hel	UAB A	Alabama B	48	10
Brodie Henry	Auburn A	Georgia Tech D	54	10
Alex Akridge	Indiana A	Notre Dame B	59	10
Shreyas Sinha	Texas B	Texas A	59	-5
Sarah Dong	Michigan C	UIC	61	10
Juliette Flatau	Imperial C	Sheffield C	61	10
Biyang Zhang	Michigan B	Chicago C	64	-5
Snehan Saroch	Louisville A	Chicago D	72	10
Jacob Finley	Notre Dame A	Michigan A	72	10
March Delfin	UCSD Two Running Violet V Forms	UCLA A	73	10
Victor Xu	Toronto H	McGill A	73	-5
Jason Zhang	Toronto B	Toronto I	73	10
Jeremy Kim	Toronto K	Ottawa	73	10
Eric Yang	Purdue A	Kentucky	73	10
Grace Early	Iowa	Tulsa	73	10
Joseph Strom	Louisville B	Notre Dame C	76	10
Cassidy McIntyre	Rose State	Ohio	76	10
Andrew Nucci	UCLA B	USC	77	10
Matthew Vidal	Northwestern C	Arizona State B	81	-5
Arvin Boraghi	Cambridge B	City St George's A	82	10
Vivian Malouf	Berkeley A	Berkeley E	83	10
Aaryan Sumesh	Berkeley D	Stanford C	83	10
Annika Larson	Claremont Scripps	UCI	83	10
Benjamin Chapman	Toronto A	McGill C	83	10
Foster Hughes	Minnesota A	Minnesota B	83	10
Jack Lewis	Bruin A	Vanderbilt A	83	10
Aisling Skeet	Durham A	Sheffield A	83	10
Nathan Easow	Manchester A	Durham B	83	10
Darren Kellis	Vanderbilt B	Georgia Tech C	85	10
Laura Bullock	Sheffield B	Imperial A	85	10
Jackson Hatcher	Nebraska	Minnesota C	86	10
Yoyo Liu	British Columbia A	British Columbia C	86	10
Jaz the Mononymous	Southampton B	Oxford B	86	10
Aarav Kakad	UCLA C	UCSB	87	10
Jonathan Ho	Alberta	British Columbia B	88	10
Anne Fjeld	Alberta B	UCO	88	10
Felix Garrett Johnston	Huntsville A	Huntsville B	88	10
Akshansh Chauhan	UTD A	UTD B	89	10
Albert Nyang	LSE A	Imperial B	89	10
Ellen Ge	Toronto E	Queen's B	91	10
Aarnav Vyas	Illinois B	Notre Dame D	92	10
Sharath Narayan	Northwestern A	Northwestern B	92	10
Sarah Silverman	Claremont Pitzer	UCSD What Hath God Wrought	94	10
Zoe Wang	Carleton	Macalester B	94	10
Krishay Garg	UCLA D	UCSD Vices and Virtues	96	10
Lee Huynh	Guelph B	Toronto F	96	-5
Charlotte Wilcox	Western Ontario	Toronto Metropolitan	96	10
Drew Wetterlind	Iowa State	Wisconsin	96	10
Jake Wingfield	Bristol B	Cambridge C	96	10
Nabhaan Farooqi	McGill B	Toronto D	97	10
Richard Lin	Washington B	Simon Fraser	97	10
Liam Buck	St. Thomas	Macalester A	98	10
Harris Beckner	Alabama A	Mississippi State A	102	10
Misty Chen	Purdue B	Illinois C	105	-5
Zaire Gibbons	Toronto J	Waterloo	106	-5
Matthew Andersen	UF A	UF E	108	10
Yaj Jhajhria	Washington A	British Columbia D	111	0
Coy Mier	Auburn B	Sewanee A	113	10
Michał Gerasimiuk	Stanford A	Berkeley B	114	10
Samuel Zheng	Toronto F	Guelph B	114	10
Galen Mueller	McGill A	Toronto H	114	10
Eva Mandelbaum	Guelph A	McMaster B	114	10
Cori Zhong	Waterloo	Toronto J	114	10
Matthew Evans	UF B	FIU	114	10
Sasha Tripathi	Chicago C	Michigan B	114	10
Raymond Jiang	Illinois C	Purdue B	114	10
Matthew He	Texas A	Texas B	114	10
Luke Houtz	Arizona State B	Northwestern C	114	10

2025 ACF Nationals

2025-08-09

100%

78.11

Canada

Main

100%

85.00

Florida

Main

100%

33%

85.75

Great Lakes

Main

100%

89.00

Overflow

Main

100%

41.00

California

Main

100%

25%

80.00

South Central

Main

100%

91.40

Main

75%

25%

90.33

Upper Mid-Atlantic

Main

100%

25%

85.75

Upstate NY

Main

100%

76.50

Pacific Northwest

Main

100%

20%

77.40

Player

Team

Opponent

Buzz Position

Value

Abby Smith

Berkeley B

Stanford A

-5

Michael Xu

McMaster C

Toronto C

Russell Nip

British Columbia D

Washington A

-5

Yusuf Baig

McMaster A

Carleton

Joel Dicker

Southampton A

Oxford A

Tianyu Xu

Georgia Tech A

Georgia Tech B

Aatreyo Bhattacharyya

Berkeley C

Stanford B

Thomas Brittain

McMaster B

Guelph A

-5

Bryan Ugaz

Arizona State A

McGill D

Braxton Davis

Missouri A

WashU A

Samarth Ram

Chicago B

Purdue C

Shiva Tegulla

UCF A

UCF B

Jakub Hel

UAB A

Alabama B

Brodie Henry

Auburn A

Georgia Tech D

Alex Akridge

Indiana A

Notre Dame B

Shreyas Sinha

Texas B

Texas A

-5

Sarah Dong

Michigan C

UIC

Juliette Flatau

Imperial C

Sheffield C

Biyang Zhang

Michigan B

Chicago C

-5

Snehan Saroch

Louisville A

Chicago D

Jacob Finley

Notre Dame A

Michigan A

March Delfin

UCSD Two Running Violet V Forms

UCLA A

Victor Xu

Toronto H

McGill A

-5

Jason Zhang

Toronto B

Toronto I

Jeremy Kim

Toronto K

Ottawa

Eric Yang

Purdue A

Kentucky

Grace Early

Iowa

Tulsa

Joseph Strom

Louisville B

Notre Dame C

Cassidy McIntyre

Rose State

Ohio

Andrew Nucci

UCLA B

USC

Matthew Vidal

Northwestern C

Arizona State B

-5

Arvin Boraghi

Cambridge B

City St George's A

Vivian Malouf

Berkeley A

Berkeley E

Aaryan Sumesh

Berkeley D

Stanford C

Annika Larson

Claremont Scripps

UCI

Benjamin Chapman

Toronto A

McGill C

Foster Hughes

Minnesota A

Minnesota B

Jack Lewis

Bruin A

Vanderbilt A

Aisling Skeet

Durham A

Sheffield A

Nathan Easow

Manchester A

Durham B

Darren Kellis

Vanderbilt B

Georgia Tech C

Laura Bullock

Sheffield B

Imperial A

Jackson Hatcher

Nebraska

Minnesota C

Yoyo Liu

British Columbia A

British Columbia C

Jaz the Mononymous

Southampton B

Oxford B

Aarav Kakad

UCLA C

UCSB

Jonathan Ho

Alberta

British Columbia B

Anne Fjeld

Alberta B

UCO

Felix Garrett Johnston

Huntsville A

Huntsville B

Akshansh Chauhan

UTD A

UTD B

Albert Nyang

LSE A

Imperial B

Ellen Ge

Toronto E

Queen's B

Aarnav Vyas

Illinois B

Notre Dame D

Sharath Narayan

Northwestern A

Northwestern B

Sarah Silverman

Claremont Pitzer

UCSD What Hath God Wrought

Zoe Wang

Carleton

Macalester B

Krishay Garg

UCLA D

UCSD Vices and Virtues

Lee Huynh

Guelph B

Toronto F

-5

Charlotte Wilcox

Western Ontario

Toronto Metropolitan

Drew Wetterlind

Iowa State

Wisconsin

Jake Wingfield

Bristol B

Cambridge C

Nabhaan Farooqi

McGill B

Toronto D

Richard Lin

Washington B

Simon Fraser

Liam Buck

St. Thomas

Macalester A

Harris Beckner

Alabama A

Mississippi State A

102

Misty Chen

Purdue B

Illinois C

105

-5

Zaire Gibbons

Toronto J

Waterloo

106

-5

Matthew Andersen

UF A

UF E

108

Yaj Jhajhria

Washington A

British Columbia D

111

Coy Mier

Auburn B

Sewanee A

113

Michał Gerasimiuk

Stanford A

Berkeley B

114

Samuel Zheng

Toronto F

Guelph B

114

Galen Mueller

McGill A

Toronto H

114

Eva Mandelbaum

Guelph A

McMaster B

114

Cori Zhong

Waterloo

Toronto J

114

Matthew Evans

UF B

FIU

114

Sasha Tripathi

Chicago C

Michigan B

114

Raymond Jiang

Illinois C

Purdue B

114

Matthew He

Texas A

Texas B

114

Luke Houtz

Arizona State B

Northwestern C

114