immortal - 2025 ACF Fall - Buzzpoints App

Question

Note to moderator: Read the answerline carefully. Note to players: Description acceptable. The first cell line with this trait was generated using tissue collected from patient Henrietta Lacks without her consent. For 10 points each:

[10h] Identify this trait characteristic of cell lines like HEK 293 (“heck 2-9-3”) and HeLa (“HE-la”). Leonard Hayflick’s research on human fetal cells refuted a long-standing dogma that all cultured cells have this trait.

ANSWER: immortal [accept immortalized cell lines; accept word forms such as immortalization; accept descriptions that indicate proliferating indefinitely or dividing indefinitely or living forever; prompt on BUT DO NOT REVEAL cancerous by asking “what trait does that confer?”; reject answers indicating “reproduction”]

[10e] Immortalized cell lines like HeLa can be generated from cells affected by this broad condition, whose tumors can spread throughout the body during metastasis.

ANSWER: cancers [accept specific types like cervical cancer; accept word forms like cancerous]

[10m] Cells can also be immortalized through the expression of an enzyme that prevents the shortening of these structures. These structures contain many “TTAGGG” repeats and cap the ends of chromosomes.

ANSWER: telomeres [prompt on telomerases]

<Editors, Biology>

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Summary


Northern California	Main	Y	4	30.00	100%	100%	100%
Southern California	Main	Y	7	25.71	100%	100%	57%
Eastern Canada (1)	Main	Y	4	22.50	100%	100%	25%
Eastern Canada (2)	Main	Y	9	23.33	100%	67%	67%
Florida	Main	Y	4	25.00	100%	100%	50%
Great Lakes	Main	Y	11	24.55	100%	91%	55%
Lower Mid-Atlantic	Main	Y	9	25.56	100%	100%	56%
Upper Mid-Atlantic	Main	Y	9	21.11	100%	67%	44%
Midwest	Main	Y	9	24.44	100%	78%	67%
North	Main	Y	4	25.00	100%	75%	75%
Pacific	Main	Y	8	22.50	100%	100%	25%
South Central	Main	Y	6	23.33	83%	83%	67%
Southeast	Main	Y	12	22.50	100%	83%	42%
UK (North)	UK	Y	5	16.00	100%	40%	20%
UK (South)	UK	Y	8	21.25	100%	88%	25%
Upstate NY	Main	Y	1	30.00	100%	100%	100%

Data


Berkeley Mighty Miner	Berkeley Boss Bandit	10	10	10	30
Berkeley Skeleton King	UCSC	10	10	10	30
USC A	Claremont C	10	10	10	30
Claremont B	UC Santa Barbara	0	10	10	20
Claremont A	UCLA A	0	10	10	20
UCLA B	UCLA C	10	10	10	30
UCSD A	UCLA E	10	10	10	30
UCSD B	UCLA F	10	10	10	30
UCLA D	USC B	0	10	10	20
Ottawa B	Carleton A	10	10	10	30
McGill E	Carleton B	0	10	10	20
McGill B	Ottawa C	0	10	10	20
Ottawa A	Ottawa D	0	10	10	20
Toronto A	Guelph A	0	10	10	20
McMaster A	Toronto C	10	10	10	30
Waterloo A	McMaster B	0	10	10	20
Toronto B	Queen's A	10	10	10	30
Waterloo C	Toronto E	10	10	10	30
Toronto F	Brock A	10	10	10	30
Toronto H	Toronto D	0	10	0	10
Toronto G	Toronto I	10	10	0	20
Waterloo B	McMaster C	10	10	0	20
Berkeley Archer Queen	Stanford A	10	10	10	30
Berkeley Little Prince	Stanford B	10	10	10	30
Florida A	Florida Tech B	0	10	10	20
Florida State A	ERAU Daytona A	0	10	10	20
Florida B	Florida Tech A	10	10	10	30
South Florida A	UCF A	10	10	10	30
CWRU D	CWRU A	10	10	10	30
Michigan C	Michigan State C	0	10	10	20
Ohio State A	Michigan D	10	10	10	30
Louisville D	Michigan State A	0	10	10	20
Ohio State C	Kentucky	0	10	0	10
Louisville B	Michigan State B	10	10	10	30
Ohio State B	Louisville C	0	10	10	20
Michigan B	Michigan State D	10	10	10	30
Pittsburgh	CWRU B	10	10	10	30
WVU A	Louisville A	0	10	10	20
WVU B	Ohio State D	10	10	10	30
Liberty B	Liberty C	0	10	10	20
JMU A	Virginia Tech B	10	10	10	30
William & Mary A	Liberty A	10	10	10	30
NCSU A	Virginia Tech C	0	10	10	20
NCSU B	UNC A	0	10	10	20
Tusculum A	VCU A	0	10	10	20
UNC B	Virginia Tech A	10	10	10	30
Virginia A	UNC D	10	10	10	30
Duke A	William & Mary C	10	10	10	30
George Mason A	Lehigh A	10	10	10	30
Maryland B	Vassar B	0	10	10	20
Maryland C	Johns Hopkins	10	10	10	30
NYU B	Princeton	10	10	0	20
Lehigh B	Rutgers A	10	10	10	30
Rutgers B	NYU C	0	10	10	20
Rutgers C	Maryland A	0	10	0	10
Rowan	Rutgers D	0	10	0	10
Stony Brook	George Mason B	0	10	10	20
Chicago A	Illinois Urbana	10	10	10	30
Purdue C	Chicago B	10	10	10	30
Purdue D	Illinois Canada	0	10	0	10
Rose-Hulman A	Illinois Champaign	0	10	10	20
Illinois Orange	Iowa A	10	10	10	30
Indiana A	Iowa B	10	10	10	30
Indiana B	Purdue A	10	10	10	30
WashU Grolars	Illinois Blue	0	10	0	10
William Woods University A	Purdue B	10	10	10	30
Minnesota	Iowa State	0	10	0	10
Wisconsin A	Wisconsin B	10	10	10	30
St. Thomas	Wisconsin C	10	10	10	30
Macalester	Michigan Tech	10	10	10	30
Arizona State A	Washington Chum	0	10	10	20
Arizona State B	Washington Atlantic	0	10	10	20
Boise State	Washington State	10	10	10	30
British Columbia A	Alberta A	0	10	10	20
British Columbia B	Washington Steelhead	0	10	10	20
Texas	Washington Chinook	10	10	10	30
Washington Pink	British Columbia C	0	10	10	20
Washington Sockeye	Alberta B	0	10	10	20
Kansas State A	Rose State	10	10	10	30
Murray State College B	Kansas State B	10	10	10	30
Murray State College A	Nebraska A	0	10	10	20
Oklahoma	Nebraska B	10	10	10	30
Harding	Tulsa A	10	0	10	20
Central Oklahoma A	Tulsa B	0	10	0	10
Alabama A	South Carolina A	10	10	10	30
Clemson A	Georgia Tech A	10	10	10	30
Georgia Tech D	Clemson C	0	10	10	20
Georgia A	Tennessee B	0	10	10	20
Georgia Tech E	Georgia Tech B	0	10	0	10
Georgia Tech C	Emory A	10	10	10	30
Georgia Tech F	Mississippi State A	0	10	10	20
Vanderbilt B	Montevallo	10	10	10	30
Clemson B	Sewanne	10	10	10	30
Chipola College	Tennessee Tech	0	10	10	20
Vanderbilt A	Tennessee A	0	10	10	20
Auburn C	Vanderbilt C	0	10	0	10
Durham D	Durham A	0	10	0	10
Durham B	Durham C	0	10	10	20
Edinburgh B	Edinburgh D	10	10	10	30
Edinburgh A	Sheffield B	0	10	0	10
York	Sheffield A	0	10	0	10
Cambridge D	Cambridge B	0	10	10	20
Cambridge E	Cambridge C	0	10	10	20
Imperial A	Imperial C	0	10	10	20
Imperial D	Cambridge A	10	10	10	30
Oxford	Birmingham	0	10	0	10
Warwick	Bristol	0	10	10	20
RIT A	Cornell D	10	10	10	30
Cardiff	LSE	10	10	10	30
Imperial B	Southampton	0	10	10	20