smallpox inoculation - 2025 ACF Winter

Question

Description acceptable. After he demonstrated this practice for her, Dowager Empress Maria of Russia gave the foundling Anton Petrov a new (10[1])name referencing it. Biographer John Baron (10[2])may have originated a myth about Sarah Nelmes’s (10[1])role in the origin of this practice. (10[1])To promote this practice (10[1])in Vienna, (10[2])Maria (10[1])Theresa (10[8]-5[1])hosted (10[3])65 (10[1])commoners (10[7]-5[2])for a royal banquet (10[1]-5[1])at the (10[1])Schönbrunn palace. (10[6]-5[3])Caroline (10[1])of Ansbach (10[1]-5[1])helped popularize this practice after being shown it (10[1])by Lady (-5[1])Mary (10[1])Wortley (10[3])Montagu, (10[8]-5[3])who introduced (10[1])it (10[3])to Europe (10[2])after (-5[1])witnessing (-5[1])it (-5[1])in the Ottoman (10[2])Empire. (10[4]-5[2])Catherine (10[1]-5[1])the Great gave (10[2]-5[1])Thomas Dimsdale (10[4])a title for performing this practice (10[1])on her by grating pustules (10[3])into (-5[1])an open (10[2])wound. (10[3])For (10[1])10 points, (10[3])the development (10[2])of what (-5[1])medical (10[1])practice in 18th-century (10[1])Europe (10[2])is often credited to Edward (-5[1])Jenner? (10[4]0[2])■END■ (10[19]0[5])

ANSWER: smallpox inoculation [accept equivalents like smallpox vaccination or smallpox variolation; prompt on inoculation, vaccination, or variolation by asking “against what disease?”; reject answers like “treatment of smallpox”] (Sarah Nelmes is the milkmaid Jenner is supposed to have seen without any smallpox lesions. Anton Petrov was renamed Anton Vaccinoff – and given a house and an income – after he received the vaccine to demonstrate its safety.)

<Editors, European History>

= Average correct buzz position

Summary


Northern California	Main	Y	5	60%	0%	40%	41.00
Southern California	Main	Y	5	100%	0%	0%	76.20
Eastern Canada	Main	Y	13	100%	0%	15%	83.69
Florida	Main	Y	6	83%	0%	0%	90.20
Great Lakes	Main	Y	7	100%	0%	0%	86.57
Lower Mid-Atlantic	Main	Y	10	100%	0%	20%	94.30
Upper Mid-Atlantic (1)	Main	Y	11	100%	0%	9%	90.55
Upper Mid-Atlantic (2)	Main	Y	5	80%	0%	60%	100.50
Lower Midwest	Main	Y	4	100%	0%	0%	70.25
Upper Midwest	Main	Y	12	100%	0%	17%	79.67
North	Main	Y	2	100%	0%	0%	64.50
Northeast	Main	Y	11	100%	0%	18%	86.82
Northwest	Main	Y	4	100%	0%	0%	68.25
Southeast	Main	Y	8	100%	0%	50%	106.00
UK	Main	Y	10	100%	0%	30%	86.50
Upstate NY	Main	Y	3	67%	0%	33%	89.50
Upstate NY	Main	Y	1	100%	0%	0%	94.00

Buzzes

Player	Team	Opponent	Buzz Position	Value
Joshua Koch	Michigan A	Illinois A	20	10
Vikram Narasimhan	Stanford C	UCSC	26	10
Arvin Boraghi	Cambridge B	Birmingham A	26	10
Emily Kadolph	Virginia Tech A	Liberty C	34	10
Isaac Studley	Carleton	Minnesota A	41	10
Sky Li	Toronto A	Ottawa	45	10
Nathaniel Hull	Berkeley B	Berkeley A	47	10
Kelvin Ni	NYU B	UMBC A	47	10
Cole Hartung	Georgetown A	Maryland A	48	10
Sam McNamee	Notre Dame A	UIC	49	10
Megan Wang	Brown A	BU	49	10
Maggie Sun	MIT B	Amherst A	49	10
Jackson Slaughter	Tennessee A	Virginia A	49	10
Sriram Susarla	British Columbia C	British Columbia B	49	10
Terrence Han	UCLA D	UCLA C	49	10
Nabhaan Farooqi	McGill B	Toronto I	49	10
Jacob Hardin-Bernhardt	NYU A	Johns Hopkins A	49	10
Mats Miller	Chicago B	Purdue A	49	-5
Jacob Ergueta	UF B	UF D	50	10
Allan Lee	Stanford B	Stanford A	50	10
Kevin Le	Carleton	McMaster C	50	10
Peter Zeng	OSU D	CWRU A	51	10
Lucas Guan	Brown B	Amherst B	52	10
Jon Suh	Harvard	Brown C	52	-5
Kevin Peng	Cornell-UG	Yale A	52	10
Olin Bose	Columbia A	Lehigh A	52	10
Tate Osborne	Auburn A	Vanderbilt A	52	-5
Kai Madgwick	Manchester A	Imperial C	52	10
Isaac Millians	USC	UCSD Two Running Violet V Forms	52	10
Sean Gao	Toronto K	McGill C	52	10
Liam Markland	Alberta	Washington B	52	10
Ryan Sun	Berkeley D	Berkeley C	56	-5
Braden Booth	Missouri A	WashU B	56	10
Sasha Fillbrandt	Washington A	Simon Fraser	58	10
Deepanshi Matai	Toronto C	Guelph A	60	10
Ben Wismath	Toronto B	Toronto D	60	10
Tommy Donelon	Missouri B	Truman State	60	10
John John Groger	WashU A	William Woods	60	10
Doug Frederick	Auburn B	Vanderbilt B	60	-5
Abdelrahman Elsisi	Sheffield A	Cambridge D	60	-5
Elliot Cosnett	Oxford A	Sheffield C	60	10
Cameron Ricketts	Warwick A	Oxford B	60	10
Misbah Meghani	UAB A	Huntsville B	60	-5
Olivia Kiser	Kentucky	Chicago C	61	10
Eugene Kim	Purdue C	Notre Dame D	63	10
Derrick Liu	Johns Hopkins B	George Washington B	63	-5
William Houston	Chicago A	Michigan B	71	10
Aarav Vasanthan	Rutgers C	Swarthmore A	73	-5
Gus Vanskike	Maryland B	Johns Hopkins C	74	10
Reed Sexton	Michigan C	Louisville A	75	10
Jim Fan	North Carolina A	Liberty B	75	10
Hamish Campbell	Durham A	Southampton B	75	10
Peyton Legg	UCF B	USF	76	10
Matthew Lam	OSU A	Pitt A	76	10
Jacob Goodson	OSU B	MSU A	76	10
Ben Lanahan	Clemson A	Virginia B	76	-5
Sam Kemeny	Brandeis Clemenceau	MIT A	76	10
Seth Allen	McMaster A	McGill A	76	-5
Ian Theysmeyer	Queen's A	Toronto H	76	10
Gabriel Avrahami	Georgetown B	Catholic University	76	10
Arhith Dharanendra	Georgia Tech D	Georgia Tech A	76	10
Daniel Hobba	Cambridge C	Edinburgh A	76	-5
Zach Tseng	Georgia Tech B	Sewanee A	76	10
Gary Lin	UCSD What Hath God Wrought	UCLA B	78	10
Pranaav Senthilkumar	Cornell-DII	Binghamton B	79	10
Sarah Khan	Queen's B	Waterloo	79	10
Matthew Amante	Notre Dame C	Chicago D	79	10
Jack Lewis	Bruin A	Alabama A	81	10
Zachary Foster	City St George's A	Imperial A	81	10
Felix Garrett Johnston	Huntsville A	Georgia Tech C	82	-5
Albert Nyang	LSE A	Bristol B	83	-5
Michael Ai	Williams	Dartmouth	84	-5
Tiffany Zhou	OSU C	CWRU B	87	10
Jeffery Austin	North Carolina B	North Carolina C	87	10
Peter Ballas	Michigan D	Indiana B	88	-5
Anurag Shah	Indiana B	Michigan D	88	10
Jacob Chambers	Iowa State	Macalester B	88	10
Beverly Eborn	BC A	Brandeis Orlando	88	10
Ben Spirtas	Maryland C	VCU A	88	10
Rahul Rao-Pothuraju	Rowan A	Vassar A	88	-5
Isaac Meredith	Tufts B	Brandeis Lloyd George	89	10
Hafsa Shaikh	Toronto G	Toronto J	89	-5
Vinu Harihar	Berkeley F	Berkeley E	92	-5
Trey Lewis	South Carolina A	Virginia Tech B	92	10
Karthik Jayaram	UCLA A	UCI	92	10
August Szpak	CWRU C	Kenyon B	94	10
Jacob Evans	MSU B	Pitt B	94	10
Cade Reinberger	RIT B	ESF	94	10
John Mitnik	Columbia B	Princeton A	94	10
Owen Linder	Binghamton A	Rochester	100	10
Alex Akridge	Indiana A	Illinois C	105	10
Aneesh Shrotriya	Purdue B	Louisville B	105	10
Conner Yamnitz	WashU C	SIUE	105	10
Abbott Sherwin	NC State	South Carolina B	106	-5
Kyan van Beek	UF C	FIU	108	10
Nicholas Nguyen	UF E	FSU	108	10
Aidan Bernardo	Melbourne B	UCF A	109	10
Leonard Castine	Penn B	George Mason C	109	10
Nathan Redford	Liberty A	James Madison	109	10
Sarah Silverman	Claremont Pitzer	UCSB	110	10
Adam Hermann	Notre Dame B	Illinois B	112	10
Charlotte Wilcox	Western Ontario	McMaster B	112	10
Virginia Stewart	Alabama B	Mississippi State A	112	10
Justin Qian	British Columbia A	British Columbia D	114	10
Gannon Rice	Clemson B	Tusculum	114	10
Jensen Tebbe	Columbia C	Lehigh B	116	-5
Christopher Dech	Brandeis Wilson	BC B	117	10
Monish Jampala	Georgia Tech C	Huntsville A	120	10
Blake Kim-Wansbrough	Toronto E	Guelph B	121	10
Aaron Henry	Maryland D	George Mason A	121	10
Danny Cutbill	RIT A	Syracuse	126	-5
Aatreyo Bhattacharyya	Berkeley C	Berkeley D	127	0
Rishabh Dave	Berkeley E	Berkeley F	127	0
Will Zhang	Tufts A	Bowdoin B	127	10
Brayden Zhang	Vanderbilt B	Auburn B	127	10
Zosia Mikołajczuk	Southampton A	Durham B	127	10
John McQueen	South Carolina B	NC State	127	10
Niru Shakya	Melbourne A	UF A	128	0
Kyle Chua	CWRU D	Kenyon A	128	0
Ethan White	Kenyon A	CWRU D	128	10
Simon Burstein	Virginia B	Clemson A	128	10
Grace Ma	Brown C	Harvard	128	10
Rajiv Pujara	Dartmouth	Williams	128	10
Daniel Griffaton	Syracuse	RIT A	128	0
Galen Mueller	McGill A	McMaster A	128	10
Ishan Joshi	Toronto Metropolitan	Toronto F	128	0
Imtiaz Kidwai	Toronto F	Toronto Metropolitan	128	10
Danny Tran	Tennessee B	Roanoke	128	10
Aidan Ross	George Washington B	Johns Hopkins B	128	10
Lauren Edgar	Lehigh B	Columbia C	128	10
Gavin Markoff	Vanderbilt A	Auburn A	128	10
Ella Keavy	Bristol B	LSE A	128	10
Ted Harrison	Edinburgh A	Cambridge C	128	10
Sam Eddon	Cambridge D	Sheffield A	128	10
James Fan	Toronto J	Toronto G	128	10
Joe O'Connor	George Mason B	Penn A	128	10
Taaj Rai	George Washington A	Notre Dame E	128	10
Ben Hellman	Swarthmore A	Rutgers C	128	10
Eli Young	Vassar A	Rowan A	128	0
Nolan Jones	Purdue A	Chicago B	128	10
Jason Hatfield	Huntsville B	UAB A	128	10

Northern California

Main

60%

40%

41.00

Southern California

Main

100%

76.20

Eastern Canada

Main

100%

15%

83.69

Florida

Main

83%

90.20

Great Lakes

Main

100%

86.57

Lower Mid-Atlantic

Main

100%

20%

94.30

Upper Mid-Atlantic (1)

Main

100%

90.55

Upper Mid-Atlantic (2)

Main

80%

60%

100.50

Lower Midwest

Main

100%

70.25

Upper Midwest

Main

100%

17%

79.67

North

Main

100%

64.50

Northeast

Main

100%

18%

86.82

Northwest

Main

100%

68.25

Southeast

Main

100%

50%

106.00

Main

100%

30%

86.50

Upstate NY

Main

67%

33%

89.50

Upstate NY

Main

100%

94.00

Player

Team

Opponent

Buzz Position

Value

Joshua Koch

Michigan A

Illinois A

Vikram Narasimhan

Stanford C

UCSC

Arvin Boraghi

Cambridge B

Birmingham A

Emily Kadolph

Virginia Tech A

Liberty C

Isaac Studley

Carleton

Minnesota A

Sky Li

Toronto A

Ottawa

Nathaniel Hull

Berkeley B

Berkeley A

Kelvin Ni

NYU B

UMBC A

Cole Hartung

Georgetown A

Maryland A

Sam McNamee

Notre Dame A

UIC

Megan Wang

Brown A

Maggie Sun

MIT B

Amherst A

Jackson Slaughter

Tennessee A

Virginia A

Sriram Susarla

British Columbia C

British Columbia B

Terrence Han

UCLA D

UCLA C

Nabhaan Farooqi

McGill B

Toronto I

Jacob Hardin-Bernhardt

NYU A

Johns Hopkins A

Mats Miller

Chicago B

Purdue A

-5

Jacob Ergueta

UF B

UF D

Allan Lee

Stanford B

Stanford A

Kevin Le

Carleton

McMaster C

Peter Zeng

OSU D

CWRU A

Lucas Guan

Brown B

Amherst B

Jon Suh

Harvard

Brown C

-5

Kevin Peng

Cornell-UG

Yale A

Olin Bose

Columbia A

Lehigh A

Tate Osborne

Auburn A

Vanderbilt A

-5

Kai Madgwick

Manchester A

Imperial C

Isaac Millians

USC

UCSD Two Running Violet V Forms

Sean Gao

Toronto K

McGill C

Liam Markland

Alberta

Washington B

Ryan Sun

Berkeley D

Berkeley C

-5

Braden Booth

Missouri A

WashU B

Sasha Fillbrandt

Washington A

Simon Fraser

Deepanshi Matai

Toronto C

Guelph A

Ben Wismath

Toronto B

Toronto D

Tommy Donelon

Missouri B

Truman State

John John Groger

WashU A

William Woods

Doug Frederick

Auburn B

Vanderbilt B

-5

Abdelrahman Elsisi

Sheffield A

Cambridge D

-5

Elliot Cosnett

Oxford A

Sheffield C

Cameron Ricketts

Warwick A

Oxford B

Misbah Meghani

UAB A

Huntsville B

-5

Olivia Kiser

Kentucky

Chicago C

Eugene Kim

Purdue C

Notre Dame D

Derrick Liu

Johns Hopkins B

George Washington B

-5

William Houston

Chicago A

Michigan B

Aarav Vasanthan

Rutgers C

Swarthmore A

-5

Gus Vanskike

Maryland B

Johns Hopkins C

Reed Sexton

Michigan C

Louisville A

Jim Fan

North Carolina A

Liberty B

Hamish Campbell

Durham A

Southampton B

Peyton Legg

UCF B

USF

Matthew Lam

OSU A

Pitt A

Jacob Goodson

OSU B

MSU A

Ben Lanahan

Clemson A

Virginia B

-5

Sam Kemeny

Brandeis Clemenceau

MIT A

Seth Allen

McMaster A

McGill A

-5

Ian Theysmeyer

Queen's A

Toronto H

Gabriel Avrahami

Georgetown B

Catholic University

Arhith Dharanendra

Georgia Tech D

Georgia Tech A

Daniel Hobba

Cambridge C

Edinburgh A

-5

Zach Tseng

Georgia Tech B

Sewanee A

Gary Lin

UCSD What Hath God Wrought

UCLA B

Pranaav Senthilkumar

Cornell-DII

Binghamton B

Sarah Khan

Queen's B

Waterloo

Matthew Amante

Notre Dame C

Chicago D

Jack Lewis

Bruin A

Alabama A

Zachary Foster

City St George's A

Imperial A

Felix Garrett Johnston

Huntsville A

Georgia Tech C

-5

Albert Nyang

LSE A

Bristol B

-5

Michael Ai

Williams

Dartmouth

-5

Tiffany Zhou

OSU C

CWRU B

Jeffery Austin

North Carolina B

North Carolina C

Peter Ballas

Michigan D

Indiana B

-5

Anurag Shah

Indiana B

Michigan D

Jacob Chambers

Iowa State

Macalester B

Beverly Eborn

BC A

Brandeis Orlando

Ben Spirtas

Maryland C

VCU A

Rahul Rao-Pothuraju

Rowan A

Vassar A

-5

Isaac Meredith

Tufts B

Brandeis Lloyd George

Hafsa Shaikh

Toronto G

Toronto J

-5

Vinu Harihar

Berkeley F

Berkeley E

-5

Trey Lewis

South Carolina A

Virginia Tech B

Karthik Jayaram

UCLA A

UCI

August Szpak

CWRU C

Kenyon B

Jacob Evans

MSU B

Pitt B

Cade Reinberger

RIT B

ESF

John Mitnik

Columbia B

Princeton A

Owen Linder

Binghamton A

Rochester

100

Alex Akridge

Indiana A

Illinois C

105

Aneesh Shrotriya

Purdue B

Louisville B

105

Conner Yamnitz

WashU C

SIUE

105

Abbott Sherwin

NC State

South Carolina B

106

-5

Kyan van Beek

UF C

FIU

108

Nicholas Nguyen

UF E

FSU

108

Aidan Bernardo

Melbourne B

UCF A

109

Leonard Castine

Penn B

George Mason C

109

Nathan Redford

Liberty A

James Madison

109

Sarah Silverman

Claremont Pitzer

UCSB

110

Adam Hermann

Notre Dame B

Illinois B

112

Charlotte Wilcox

Western Ontario

McMaster B

112

Virginia Stewart

Alabama B

Mississippi State A

112

Justin Qian

British Columbia A

British Columbia D

114

Gannon Rice

Clemson B

Tusculum

114

Jensen Tebbe

Columbia C

Lehigh B

116

-5

Christopher Dech

Brandeis Wilson

BC B

117

Monish Jampala

Georgia Tech C

Huntsville A

120

Blake Kim-Wansbrough

Toronto E

Guelph B

121

Aaron Henry

Maryland D

George Mason A

121

Danny Cutbill

RIT A

Syracuse

126

-5

Aatreyo Bhattacharyya

Berkeley C

Berkeley D

127

Rishabh Dave

Berkeley E

Berkeley F

127

Will Zhang

Tufts A

Bowdoin B

127

Brayden Zhang

Vanderbilt B

Auburn B

127

Zosia Mikołajczuk

Southampton A

Durham B

127

John McQueen

South Carolina B

NC State

127

Niru Shakya

Melbourne A

UF A

128

Kyle Chua

CWRU D

Kenyon A

128

Ethan White

Kenyon A

CWRU D

128

Simon Burstein

Virginia B

Clemson A

128

Grace Ma

Brown C

Harvard

128

Rajiv Pujara

Dartmouth

Williams

128

Daniel Griffaton

Syracuse

RIT A

128

Galen Mueller

McGill A

McMaster A

128

Ishan Joshi

Toronto Metropolitan

Toronto F

128

Imtiaz Kidwai

Toronto F

Toronto Metropolitan

128

Danny Tran

Tennessee B

Roanoke

128

Aidan Ross

George Washington B

Johns Hopkins B

128

Lauren Edgar

Lehigh B

Columbia C

128

Gavin Markoff

Vanderbilt A

Auburn A

128

Ella Keavy

Bristol B

LSE A

128

Ted Harrison

Edinburgh A

Cambridge C

128

Sam Eddon

Cambridge D

Sheffield A

128

James Fan

Toronto J

Toronto G

128

Joe O'Connor

George Mason B

Penn A

128

Taaj Rai

George Washington A

Notre Dame E

128

Ben Hellman

Swarthmore A

Rutgers C

128

Eli Young

Vassar A

Rowan A

128

Nolan Jones

Purdue A

Chicago B

128

Jason Hatfield

Huntsville B

UAB A

128