An enzyme that primarily degrades this protein forces substrates to refold into beta-sheets in a triangular prism-shaped active site. Two disulfide bonds stabilize the two chains of this protein, which originate from cleavage of a single precursor that assembles into hexameric complexes that coordinate to zinc. This protein propagates signals after binding a receptor tyrosine kinase that triggers the PI3K and ERK pathways. Intracellular vesicles sensitive to this protein express the protein GLUT4. Amylin and this hormone are produced in the islets of Langerhans in beta cells of the pancreas. This hormone promotes the formation of glycogen. For 10 points, name this peptide hormone that promotes absorption of glucose that is deficient in diabetes. ■END■
| Northern California | Main | Y | 4 | 100% | 0% | 25% | 80.00 |
| Southern California | Main | Y | 6 | 100% | 0% | 0% | 85.00 |
| Eastern Canada | Main | Y | 12 | 100% | 0% | 33% | 85.75 |
| Florida | Main | Y | 3 | 100% | 0% | 0% | 89.00 |
| Lower Midwest | Main | Y | 1 | 100% | 0% | 0% | 41.00 |
| Upper Midwest | Main | Y | 10 | 100% | 0% | 20% | 77.40 |
| North | Main | Y | 5 | 100% | 0% | 0% | 91.40 |
| Northwest | Main | Y | 4 | 75% | 0% | 25% | 90.33 |
| South Central | Main | Y | 8 | 100% | 0% | 25% | 85.75 |
| Southeast | Main | Y | 8 | 100% | 0% | 0% | 76.50 |
| UK | Main | Y | 9 | 100% | 0% | 0% | 78.11 |
| Player | Team | Opponent | Buzz Position | Value |
|---|---|---|---|---|
| Michael Xu | McMaster C | Toronto C | 28 | 10 |
| Russell Nip | British Columbia D | Washington A | 28 | -5 |
| Abby Smith | Berkeley B | Stanford A | 28 | -5 |
| Yusuf Baig | McMaster A | Carleton | 32 | 10 |
| Joel Dicker | Southampton A | Oxford A | 38 | 10 |
| Tianyu Xu | Georgia Tech A | Georgia Tech B | 39 | 10 |
| Thomas Brittain | McMaster B | Guelph A | 40 | -5 |
| Bryan Ugaz | Arizona State A | McGill D | 40 | 10 |
| Aatreyo Bhattacharyya | Berkeley C | Stanford B | 40 | 10 |
| Braxton Davis | Missouri A | WashU A | 41 | 10 |
| Samarth Ram | Chicago B | Purdue C | 41 | 10 |
| Shiva Tegulla | UCF A | UCF B | 45 | 10 |
| Jakub Hel | UAB A | Alabama B | 48 | 10 |
| Brodie Henry | Auburn A | Georgia Tech D | 54 | 10 |
| Shreyas Sinha | Texas B | Texas A | 59 | -5 |
| Alex Akridge | Indiana A | Notre Dame B | 59 | 10 |
| Sarah Dong | Michigan C | UIC | 61 | 10 |
| Juliette Flatau | Imperial C | Sheffield C | 61 | 10 |
| Biyang Zhang | Michigan B | Chicago C | 64 | -5 |
| Snehan Saroch | Louisville A | Chicago D | 72 | 10 |
| Jacob Finley | Notre Dame A | Michigan A | 72 | 10 |
| Victor Xu | Toronto H | McGill A | 73 | -5 |
| Jason Zhang | Toronto B | Toronto I | 73 | 10 |
| Jeremy Kim | Toronto K | Ottawa | 73 | 10 |
| Grace Early | Iowa | Tulsa | 73 | 10 |
| March Delfin | UCSD Two Running Violet V Forms | UCLA A | 73 | 10 |
| Eric Yang | Purdue A | Kentucky | 73 | 10 |
| Cassidy McIntyre | Rose State | Ohio | 76 | 10 |
| Joseph Strom | Louisville B | Notre Dame C | 76 | 10 |
| Andrew Nucci | UCLA B | USC | 77 | 10 |
| Matthew Vidal | Northwestern C | Arizona State B | 81 | -5 |
| Arvin Boraghi | Cambridge B | City St George's A | 82 | 10 |
| Benjamin Chapman | Toronto A | McGill C | 83 | 10 |
| Jack Lewis | Bruin A | Vanderbilt A | 83 | 10 |
| Aaryan Sumesh | Berkeley D | Stanford C | 83 | 10 |
| Annika Larson | Claremont Scripps | UCI | 83 | 10 |
| Foster Hughes | Minnesota A | Minnesota B | 83 | 10 |
| Vivian Malouf | Berkeley A | Berkeley E | 83 | 10 |
| Nathan Easow | Manchester A | Durham B | 83 | 10 |
| Aisling Skeet | Durham A | Sheffield A | 83 | 10 |
| Darren Kellis | Vanderbilt B | Georgia Tech C | 85 | 10 |
| Laura Bullock | Sheffield B | Imperial A | 85 | 10 |
| Jackson Hatcher | Nebraska | Minnesota C | 86 | 10 |
| Yoyo Liu | British Columbia A | British Columbia C | 86 | 10 |
| Jaz the Mononymous | Southampton B | Oxford B | 86 | 10 |
| Aarav Kakad | UCLA C | UCSB | 87 | 10 |
| Anne Fjeld | Alberta B | UCO | 88 | 10 |
| Felix Garrett Johnston | Huntsville A | Huntsville B | 88 | 10 |
| Jonathan Ho | Alberta | British Columbia B | 88 | 10 |
| Akshansh Chauhan | UTD A | UTD B | 89 | 10 |
| Albert Nyang | LSE A | Imperial B | 89 | 10 |
| Ellen Ge | Toronto E | Queen's B | 91 | 10 |
| Sharath Narayan | Northwestern A | Northwestern B | 92 | 10 |
| Aarnav Vyas | Illinois B | Notre Dame D | 92 | 10 |
| Sarah Silverman | Claremont Pitzer | UCSD What Hath God Wrought | 94 | 10 |
| Zoe Wang | Carleton | Macalester B | 94 | 10 |
| Lee Huynh | Guelph B | Toronto F | 96 | -5 |
| Charlotte Wilcox | Western Ontario | Toronto Metropolitan | 96 | 10 |
| Jake Wingfield | Bristol B | Cambridge C | 96 | 10 |
| Krishay Garg | UCLA D | UCSD Vices and Virtues | 96 | 10 |
| Drew Wetterlind | Iowa State | Wisconsin | 96 | 10 |
| Nabhaan Farooqi | McGill B | Toronto D | 97 | 10 |
| Richard Lin | Washington B | Simon Fraser | 97 | 10 |
| Liam Buck | St. Thomas | Macalester A | 98 | 10 |
| Harris Beckner | Alabama A | Mississippi State A | 102 | 10 |
| Misty Chen | Purdue B | Illinois C | 105 | -5 |
| Zaire Gibbons | Toronto J | Waterloo | 106 | -5 |
| Matthew Andersen | UF A | UF E | 108 | 10 |
| Yaj Jhajhria | Washington A | British Columbia D | 111 | 0 |
| Coy Mier | Auburn B | Sewanee A | 113 | 10 |
| Samuel Zheng | Toronto F | Guelph B | 114 | 10 |
| Galen Mueller | McGill A | Toronto H | 114 | 10 |
| Eva Mandelbaum | Guelph A | McMaster B | 114 | 10 |
| Cori Zhong | Waterloo | Toronto J | 114 | 10 |
| Matthew He | Texas A | Texas B | 114 | 10 |
| Raymond Jiang | Illinois C | Purdue B | 114 | 10 |
| Luke Houtz | Arizona State B | Northwestern C | 114 | 10 |
| Michał Gerasimiuk | Stanford A | Berkeley B | 114 | 10 |
| Matthew Evans | UF B | FIU | 114 | 10 |
| Sasha Tripathi | Chicago C | Michigan B | 114 | 10 |