An enzyme that primarily degrades this protein forces substrates to refold into beta-sheets in a triangular prism-shaped active site. Two disulfide bonds stabilize the two chains of this protein, which originate from cleavage of a single precursor that assembles into hexameric complexes that coordinate to zinc. This protein propagates signals after binding a receptor tyrosine kinase that triggers the PI3K and ERK pathways. Intracellular vesicles sensitive to this protein express the protein GLUT4. Amylin and this hormone are produced in the islets of Langerhans in beta cells of the pancreas. This hormone promotes the formation of glycogen. For 10 points, name this peptide hormone that promotes absorption of glucose that is deficient in diabetes. ■END■
| Northern California | Main | Y | 4 | 100% | 0% | 25% | 80.00 |
| Southern California | Main | Y | 6 | 100% | 0% | 0% | 85.00 |
| Eastern Canada | Main | Y | 12 | 100% | 0% | 33% | 85.75 |
| Florida | Main | Y | 3 | 100% | 0% | 0% | 89.00 |
| Lower Midwest | Main | Y | 1 | 100% | 0% | 0% | 41.00 |
| Upper Midwest | Main | Y | 10 | 100% | 0% | 20% | 77.40 |
| North | Main | Y | 5 | 100% | 0% | 0% | 91.40 |
| Northwest | Main | Y | 4 | 75% | 0% | 25% | 90.33 |
| South Central | Main | Y | 8 | 100% | 0% | 25% | 85.75 |
| Southeast | Main | Y | 8 | 100% | 0% | 0% | 76.50 |
| UK | Main | Y | 9 | 100% | 0% | 0% | 78.11 |
| Player | Team | Opponent | Buzz Position | Value |
|---|---|---|---|---|
| Michael Xu | McMaster C | Toronto C | 28 | 10 |
| Russell Nip | British Columbia D | Washington A | 28 | -5 |
| Abby Smith | Berkeley B | Stanford A | 28 | -5 |
| Yusuf Baig | McMaster A | Carleton | 32 | 10 |
| Joel Dicker | Southampton A | Oxford A | 38 | 10 |
| Tianyu Xu | Georgia Tech A | Georgia Tech B | 39 | 10 |
| Thomas Brittain | McMaster B | Guelph A | 40 | -5 |
| Bryan Ugaz | Arizona State A | McGill D | 40 | 10 |
| Aatreyo Bhattacharyya | Berkeley C | Stanford B | 40 | 10 |
| Samarth Ram | Chicago B | Purdue C | 41 | 10 |
| Braxton Davis | Missouri A | WashU A | 41 | 10 |
| Shiva Tegulla | UCF A | UCF B | 45 | 10 |
| Jakub Hel | UAB A | Alabama B | 48 | 10 |
| Brodie Henry | Auburn A | Georgia Tech D | 54 | 10 |
| Shreyas Sinha | Texas B | Texas A | 59 | -5 |
| Alex Akridge | Indiana A | Notre Dame B | 59 | 10 |
| Juliette Flatau | Imperial C | Sheffield C | 61 | 10 |
| Sarah Dong | Michigan C | UIC | 61 | 10 |
| Biyang Zhang | Michigan B | Chicago C | 64 | -5 |
| Snehan Saroch | Louisville A | Chicago D | 72 | 10 |
| Jacob Finley | Notre Dame A | Michigan A | 72 | 10 |
| March Delfin | UCSD Two Running Violet V Forms | UCLA A | 73 | 10 |
| Victor Xu | Toronto H | McGill A | 73 | -5 |
| Grace Early | Iowa | Tulsa | 73 | 10 |
| Jeremy Kim | Toronto K | Ottawa | 73 | 10 |
| Eric Yang | Purdue A | Kentucky | 73 | 10 |
| Jason Zhang | Toronto B | Toronto I | 73 | 10 |
| Cassidy McIntyre | Rose State | Ohio | 76 | 10 |
| Joseph Strom | Louisville B | Notre Dame C | 76 | 10 |
| Andrew Nucci | UCLA B | USC | 77 | 10 |
| Matthew Vidal | Northwestern C | Arizona State B | 81 | -5 |
| Arvin Boraghi | Cambridge B | City St George's A | 82 | 10 |
| Annika Larson | Claremont Scripps | UCI | 83 | 10 |
| Jack Lewis | Bruin A | Vanderbilt A | 83 | 10 |
| Vivian Malouf | Berkeley A | Berkeley E | 83 | 10 |
| Nathan Easow | Manchester A | Durham B | 83 | 10 |
| Aisling Skeet | Durham A | Sheffield A | 83 | 10 |
| Aaryan Sumesh | Berkeley D | Stanford C | 83 | 10 |
| Benjamin Chapman | Toronto A | McGill C | 83 | 10 |
| Foster Hughes | Minnesota A | Minnesota B | 83 | 10 |
| Darren Kellis | Vanderbilt B | Georgia Tech C | 85 | 10 |
| Laura Bullock | Sheffield B | Imperial A | 85 | 10 |
| Yoyo Liu | British Columbia A | British Columbia C | 86 | 10 |
| Jaz the Mononymous | Southampton B | Oxford B | 86 | 10 |
| Jackson Hatcher | Nebraska | Minnesota C | 86 | 10 |
| Aarav Kakad | UCLA C | UCSB | 87 | 10 |
| Jonathan Ho | Alberta | British Columbia B | 88 | 10 |
| Anne Fjeld | Alberta B | UCO | 88 | 10 |
| Felix Garrett Johnston | Huntsville A | Huntsville B | 88 | 10 |
| Akshansh Chauhan | UTD A | UTD B | 89 | 10 |
| Albert Nyang | LSE A | Imperial B | 89 | 10 |
| Ellen Ge | Toronto E | Queen's B | 91 | 10 |
| Sharath Narayan | Northwestern A | Northwestern B | 92 | 10 |
| Aarnav Vyas | Illinois B | Notre Dame D | 92 | 10 |
| Sarah Silverman | Claremont Pitzer | UCSD What Hath God Wrought | 94 | 10 |
| Zoe Wang | Carleton | Macalester B | 94 | 10 |
| Krishay Garg | UCLA D | UCSD Vices and Virtues | 96 | 10 |
| Lee Huynh | Guelph B | Toronto F | 96 | -5 |
| Charlotte Wilcox | Western Ontario | Toronto Metropolitan | 96 | 10 |
| Drew Wetterlind | Iowa State | Wisconsin | 96 | 10 |
| Jake Wingfield | Bristol B | Cambridge C | 96 | 10 |
| Richard Lin | Washington B | Simon Fraser | 97 | 10 |
| Nabhaan Farooqi | McGill B | Toronto D | 97 | 10 |
| Liam Buck | St. Thomas | Macalester A | 98 | 10 |
| Harris Beckner | Alabama A | Mississippi State A | 102 | 10 |
| Misty Chen | Purdue B | Illinois C | 105 | -5 |
| Zaire Gibbons | Toronto J | Waterloo | 106 | -5 |
| Matthew Andersen | UF A | UF E | 108 | 10 |
| Yaj Jhajhria | Washington A | British Columbia D | 111 | 0 |
| Coy Mier | Auburn B | Sewanee A | 113 | 10 |
| Samuel Zheng | Toronto F | Guelph B | 114 | 10 |
| Galen Mueller | McGill A | Toronto H | 114 | 10 |
| Eva Mandelbaum | Guelph A | McMaster B | 114 | 10 |
| Luke Houtz | Arizona State B | Northwestern C | 114 | 10 |
| Matthew He | Texas A | Texas B | 114 | 10 |
| Michał Gerasimiuk | Stanford A | Berkeley B | 114 | 10 |
| Cori Zhong | Waterloo | Toronto J | 114 | 10 |
| Sasha Tripathi | Chicago C | Michigan B | 114 | 10 |
| Raymond Jiang | Illinois C | Purdue B | 114 | 10 |
| Matthew Evans | UF B | FIU | 114 | 10 |