An enzyme that primarily degrades this protein forces substrates to refold into beta-sheets in a triangular prism-shaped active site. Two disulfide bonds stabilize the two chains of this protein, which originate from cleavage of a single precursor that assembles into hexameric complexes that coordinate to zinc. This protein propagates signals after binding a receptor tyrosine kinase that triggers the PI3K and ERK pathways. Intracellular vesicles sensitive to this protein express the protein GLUT4. Amylin and this hormone are produced in the islets of Langerhans in beta cells of the pancreas. This hormone promotes the formation of glycogen. For 10 points, name this peptide hormone that promotes absorption of glucose that is deficient in diabetes. ■END■
| Northern California | Main | Y | 4 | 100% | 0% | 25% | 80.00 |
| Southern California | Main | Y | 6 | 100% | 0% | 0% | 85.00 |
| Eastern Canada | Main | Y | 12 | 100% | 0% | 33% | 85.75 |
| Florida | Main | Y | 3 | 100% | 0% | 0% | 89.00 |
| Lower Midwest | Main | Y | 1 | 100% | 0% | 0% | 41.00 |
| Upper Midwest | Main | Y | 10 | 100% | 0% | 20% | 77.40 |
| North | Main | Y | 5 | 100% | 0% | 0% | 91.40 |
| Northwest | Main | Y | 4 | 75% | 0% | 25% | 90.33 |
| South Central | Main | Y | 8 | 100% | 0% | 25% | 85.75 |
| Southeast | Main | Y | 8 | 100% | 0% | 0% | 76.50 |
| UK | Main | Y | 9 | 100% | 0% | 0% | 78.11 |
| Player | Team | Opponent | Buzz Position | Value |
|---|---|---|---|---|
| Abby Smith | Berkeley B | Stanford A | 28 | -5 |
| Michael Xu | McMaster C | Toronto C | 28 | 10 |
| Russell Nip | British Columbia D | Washington A | 28 | -5 |
| Yusuf Baig | McMaster A | Carleton | 32 | 10 |
| Joel Dicker | Southampton A | Oxford A | 38 | 10 |
| Tianyu Xu | Georgia Tech A | Georgia Tech B | 39 | 10 |
| Aatreyo Bhattacharyya | Berkeley C | Stanford B | 40 | 10 |
| Thomas Brittain | McMaster B | Guelph A | 40 | -5 |
| Bryan Ugaz | Arizona State A | McGill D | 40 | 10 |
| Braxton Davis | Missouri A | WashU A | 41 | 10 |
| Samarth Ram | Chicago B | Purdue C | 41 | 10 |
| Shiva Tegulla | UCF A | UCF B | 45 | 10 |
| Jakub Hel | UAB A | Alabama B | 48 | 10 |
| Brodie Henry | Auburn A | Georgia Tech D | 54 | 10 |
| Alex Akridge | Indiana A | Notre Dame B | 59 | 10 |
| Shreyas Sinha | Texas B | Texas A | 59 | -5 |
| Sarah Dong | Michigan C | UIC | 61 | 10 |
| Juliette Flatau | Imperial C | Sheffield C | 61 | 10 |
| Biyang Zhang | Michigan B | Chicago C | 64 | -5 |
| Snehan Saroch | Louisville A | Chicago D | 72 | 10 |
| Jacob Finley | Notre Dame A | Michigan A | 72 | 10 |
| Victor Xu | Toronto H | McGill A | 73 | -5 |
| Jason Zhang | Toronto B | Toronto I | 73 | 10 |
| Jeremy Kim | Toronto K | Ottawa | 73 | 10 |
| March Delfin | UCSD Two Running Violet V Forms | UCLA A | 73 | 10 |
| Eric Yang | Purdue A | Kentucky | 73 | 10 |
| Grace Early | Iowa | Tulsa | 73 | 10 |
| Joseph Strom | Louisville B | Notre Dame C | 76 | 10 |
| Cassidy McIntyre | Rose State | Ohio | 76 | 10 |
| Andrew Nucci | UCLA B | USC | 77 | 10 |
| Matthew Vidal | Northwestern C | Arizona State B | 81 | -5 |
| Arvin Boraghi | Cambridge B | City St George's A | 82 | 10 |
| Vivian Malouf | Berkeley A | Berkeley E | 83 | 10 |
| Aaryan Sumesh | Berkeley D | Stanford C | 83 | 10 |
| Benjamin Chapman | Toronto A | McGill C | 83 | 10 |
| Jack Lewis | Bruin A | Vanderbilt A | 83 | 10 |
| Nathan Easow | Manchester A | Durham B | 83 | 10 |
| Aisling Skeet | Durham A | Sheffield A | 83 | 10 |
| Annika Larson | Claremont Scripps | UCI | 83 | 10 |
| Foster Hughes | Minnesota A | Minnesota B | 83 | 10 |
| Darren Kellis | Vanderbilt B | Georgia Tech C | 85 | 10 |
| Laura Bullock | Sheffield B | Imperial A | 85 | 10 |
| Jaz the Mononymous | Southampton B | Oxford B | 86 | 10 |
| Jackson Hatcher | Nebraska | Minnesota C | 86 | 10 |
| Yoyo Liu | British Columbia A | British Columbia C | 86 | 10 |
| Aarav Kakad | UCLA C | UCSB | 87 | 10 |
| Anne Fjeld | Alberta B | UCO | 88 | 10 |
| Felix Garrett Johnston | Huntsville A | Huntsville B | 88 | 10 |
| Jonathan Ho | Alberta | British Columbia B | 88 | 10 |
| Akshansh Chauhan | UTD A | UTD B | 89 | 10 |
| Albert Nyang | LSE A | Imperial B | 89 | 10 |
| Ellen Ge | Toronto E | Queen's B | 91 | 10 |
| Aarnav Vyas | Illinois B | Notre Dame D | 92 | 10 |
| Sharath Narayan | Northwestern A | Northwestern B | 92 | 10 |
| Sarah Silverman | Claremont Pitzer | UCSD What Hath God Wrought | 94 | 10 |
| Zoe Wang | Carleton | Macalester B | 94 | 10 |
| Charlotte Wilcox | Western Ontario | Toronto Metropolitan | 96 | 10 |
| Jake Wingfield | Bristol B | Cambridge C | 96 | 10 |
| Krishay Garg | UCLA D | UCSD Vices and Virtues | 96 | 10 |
| Lee Huynh | Guelph B | Toronto F | 96 | -5 |
| Drew Wetterlind | Iowa State | Wisconsin | 96 | 10 |
| Nabhaan Farooqi | McGill B | Toronto D | 97 | 10 |
| Richard Lin | Washington B | Simon Fraser | 97 | 10 |
| Liam Buck | St. Thomas | Macalester A | 98 | 10 |
| Harris Beckner | Alabama A | Mississippi State A | 102 | 10 |
| Misty Chen | Purdue B | Illinois C | 105 | -5 |
| Zaire Gibbons | Toronto J | Waterloo | 106 | -5 |
| Matthew Andersen | UF A | UF E | 108 | 10 |
| Yaj Jhajhria | Washington A | British Columbia D | 111 | 0 |
| Coy Mier | Auburn B | Sewanee A | 113 | 10 |
| Michał Gerasimiuk | Stanford A | Berkeley B | 114 | 10 |
| Sasha Tripathi | Chicago C | Michigan B | 114 | 10 |
| Galen Mueller | McGill A | Toronto H | 114 | 10 |
| Eva Mandelbaum | Guelph A | McMaster B | 114 | 10 |
| Cori Zhong | Waterloo | Toronto J | 114 | 10 |
| Matthew Evans | UF B | FIU | 114 | 10 |
| Samuel Zheng | Toronto F | Guelph B | 114 | 10 |
| Raymond Jiang | Illinois C | Purdue B | 114 | 10 |
| Luke Houtz | Arizona State B | Northwestern C | 114 | 10 |
| Matthew He | Texas A | Texas B | 114 | 10 |