An enzyme that primarily degrades this protein forces substrates to refold into beta-sheets in a triangular prism-shaped active site. Two disulfide bonds stabilize the two chains of this protein, which originate from cleavage of a single precursor that assembles into hexameric complexes that coordinate to zinc. This protein propagates signals after binding a receptor tyrosine kinase that triggers the PI3K and ERK pathways. Intracellular vesicles sensitive to this protein express the protein GLUT4. Amylin and this hormone are produced in the islets of Langerhans in beta cells of the pancreas. This hormone promotes the formation of glycogen. For 10 points, name this peptide hormone that promotes absorption of glucose that is deficient in diabetes. ■END■
| Northern California | Main | Y | 4 | 100% | 0% | 25% | 80.00 |
| Southern California | Main | Y | 6 | 100% | 0% | 0% | 85.00 |
| Eastern Canada | Main | Y | 12 | 100% | 0% | 33% | 85.75 |
| Florida | Main | Y | 3 | 100% | 0% | 0% | 89.00 |
| Lower Midwest | Main | Y | 1 | 100% | 0% | 0% | 41.00 |
| Upper Midwest | Main | Y | 10 | 100% | 0% | 20% | 77.40 |
| North | Main | Y | 5 | 100% | 0% | 0% | 91.40 |
| Northwest | Main | Y | 4 | 75% | 0% | 25% | 90.33 |
| South Central | Main | Y | 8 | 100% | 0% | 25% | 85.75 |
| Southeast | Main | Y | 8 | 100% | 0% | 0% | 76.50 |
| UK | Main | Y | 9 | 100% | 0% | 0% | 78.11 |
| Player | Team | Opponent | Buzz Position | Value |
|---|---|---|---|---|
| Abby Smith | Berkeley B | Stanford A | 28 | -5 |
| Michael Xu | McMaster C | Toronto C | 28 | 10 |
| Russell Nip | British Columbia D | Washington A | 28 | -5 |
| Yusuf Baig | McMaster A | Carleton | 32 | 10 |
| Joel Dicker | Southampton A | Oxford A | 38 | 10 |
| Tianyu Xu | Georgia Tech A | Georgia Tech B | 39 | 10 |
| Aatreyo Bhattacharyya | Berkeley C | Stanford B | 40 | 10 |
| Thomas Brittain | McMaster B | Guelph A | 40 | -5 |
| Bryan Ugaz | Arizona State A | McGill D | 40 | 10 |
| Braxton Davis | Missouri A | WashU A | 41 | 10 |
| Samarth Ram | Chicago B | Purdue C | 41 | 10 |
| Shiva Tegulla | UCF A | UCF B | 45 | 10 |
| Jakub Hel | UAB A | Alabama B | 48 | 10 |
| Brodie Henry | Auburn A | Georgia Tech D | 54 | 10 |
| Alex Akridge | Indiana A | Notre Dame B | 59 | 10 |
| Shreyas Sinha | Texas B | Texas A | 59 | -5 |
| Sarah Dong | Michigan C | UIC | 61 | 10 |
| Juliette Flatau | Imperial C | Sheffield C | 61 | 10 |
| Biyang Zhang | Michigan B | Chicago C | 64 | -5 |
| Snehan Saroch | Louisville A | Chicago D | 72 | 10 |
| Jacob Finley | Notre Dame A | Michigan A | 72 | 10 |
| Eric Yang | Purdue A | Kentucky | 73 | 10 |
| March Delfin | UCSD Two Running Violet V Forms | UCLA A | 73 | 10 |
| Victor Xu | Toronto H | McGill A | 73 | -5 |
| Grace Early | Iowa | Tulsa | 73 | 10 |
| Jason Zhang | Toronto B | Toronto I | 73 | 10 |
| Jeremy Kim | Toronto K | Ottawa | 73 | 10 |
| Joseph Strom | Louisville B | Notre Dame C | 76 | 10 |
| Cassidy McIntyre | Rose State | Ohio | 76 | 10 |
| Andrew Nucci | UCLA B | USC | 77 | 10 |
| Matthew Vidal | Northwestern C | Arizona State B | 81 | -5 |
| Arvin Boraghi | Cambridge B | City St George's A | 82 | 10 |
| Vivian Malouf | Berkeley A | Berkeley E | 83 | 10 |
| Foster Hughes | Minnesota A | Minnesota B | 83 | 10 |
| Aisling Skeet | Durham A | Sheffield A | 83 | 10 |
| Aaryan Sumesh | Berkeley D | Stanford C | 83 | 10 |
| Annika Larson | Claremont Scripps | UCI | 83 | 10 |
| Benjamin Chapman | Toronto A | McGill C | 83 | 10 |
| Jack Lewis | Bruin A | Vanderbilt A | 83 | 10 |
| Nathan Easow | Manchester A | Durham B | 83 | 10 |
| Darren Kellis | Vanderbilt B | Georgia Tech C | 85 | 10 |
| Laura Bullock | Sheffield B | Imperial A | 85 | 10 |
| Jackson Hatcher | Nebraska | Minnesota C | 86 | 10 |
| Jaz the Mononymous | Southampton B | Oxford B | 86 | 10 |
| Yoyo Liu | British Columbia A | British Columbia C | 86 | 10 |
| Aarav Kakad | UCLA C | UCSB | 87 | 10 |
| Jonathan Ho | Alberta | British Columbia B | 88 | 10 |
| Anne Fjeld | Alberta B | UCO | 88 | 10 |
| Felix Garrett Johnston | Huntsville A | Huntsville B | 88 | 10 |
| Akshansh Chauhan | UTD A | UTD B | 89 | 10 |
| Albert Nyang | LSE A | Imperial B | 89 | 10 |
| Ellen Ge | Toronto E | Queen's B | 91 | 10 |
| Aarnav Vyas | Illinois B | Notre Dame D | 92 | 10 |
| Sharath Narayan | Northwestern A | Northwestern B | 92 | 10 |
| Zoe Wang | Carleton | Macalester B | 94 | 10 |
| Sarah Silverman | Claremont Pitzer | UCSD What Hath God Wrought | 94 | 10 |
| Krishay Garg | UCLA D | UCSD Vices and Virtues | 96 | 10 |
| Lee Huynh | Guelph B | Toronto F | 96 | -5 |
| Drew Wetterlind | Iowa State | Wisconsin | 96 | 10 |
| Charlotte Wilcox | Western Ontario | Toronto Metropolitan | 96 | 10 |
| Jake Wingfield | Bristol B | Cambridge C | 96 | 10 |
| Richard Lin | Washington B | Simon Fraser | 97 | 10 |
| Nabhaan Farooqi | McGill B | Toronto D | 97 | 10 |
| Liam Buck | St. Thomas | Macalester A | 98 | 10 |
| Harris Beckner | Alabama A | Mississippi State A | 102 | 10 |
| Misty Chen | Purdue B | Illinois C | 105 | -5 |
| Zaire Gibbons | Toronto J | Waterloo | 106 | -5 |
| Matthew Andersen | UF A | UF E | 108 | 10 |
| Yaj Jhajhria | Washington A | British Columbia D | 111 | 0 |
| Coy Mier | Auburn B | Sewanee A | 113 | 10 |
| Michał Gerasimiuk | Stanford A | Berkeley B | 114 | 10 |
| Sasha Tripathi | Chicago C | Michigan B | 114 | 10 |
| Raymond Jiang | Illinois C | Purdue B | 114 | 10 |
| Samuel Zheng | Toronto F | Guelph B | 114 | 10 |
| Galen Mueller | McGill A | Toronto H | 114 | 10 |
| Eva Mandelbaum | Guelph A | McMaster B | 114 | 10 |
| Luke Houtz | Arizona State B | Northwestern C | 114 | 10 |
| Matthew He | Texas A | Texas B | 114 | 10 |
| Cori Zhong | Waterloo | Toronto J | 114 | 10 |
| Matthew Evans | UF B | FIU | 114 | 10 |