Question

They’re not dehydratases, but a family of enzymes that acts on this functional group frequently contains a 7-stranded antiparallel beta sheet wrapped around a 5-turn alpha helix, forming a HotDog domain. This functional group is hydrolyzed by the ACOT family of enzymes. During fatty acid and polyketide synthesis, the growing chain is linked to ACP via this functional group. (10[2]-5[3])A SEA group undergoes an (-5[1])acyl (“ASS-il”) shift to form a peptide-linked example of this functional group in situ in a variant of native chemical ligation. Citrate synthase hydrolyzes (-5[1])this group after binding to oxaloacetate in the first step of the Krebs cycle. (-5[1])Coenzyme A is often linked to (-5[1])fatty acids (10[1])via (-5[1])this functional group. (-5[3])For 10 points, name this functional group consisting of a sulfur atom (-5[1])linking an acyl (“ASS-il”) group and an (-5[1])R group. (10[2])■END■ (10[6]0[10])

ANSWER: thioesters [reject “esters” or “thiols”]
<Chemistry>
= Average correct buzz position

Summary

2025 ACF Nationals04/19/2025Y2152%0%62%116.91

Buzzes

PlayerTeamOpponentBuzz PositionValue
Alex AkridgeIndianaFlorida58-5
Russell NipBritish ColumbiaMinnesota58-5
Bryan UgazArizona StateTexas5810
Aiden DartleyRutgersIllinois A5810
Yashwanth BajjiMichiganWUSTL B58-5
James WangOttawaLSE63-5
Caleb OttWaterloo BNorth Carolina B86-5
Ryan SunUC Berkeley BNorthwestern100-5
Shiva TegullaUCFGeorgia State106-5
Allan LeeStanfordVirginia Tech10810
Richard NiuCornell AVanderbilt109-5
Calvin BostlemanOhio StateJohns Hopkins112-5
Ian LuGeorgia TechUC Berkeley A112-5
Derek ChenColumbia BToronto A112-5
Joseph ChambersVirginiaChicago B124-5
Alan XieYaleIowa State130-5
Joy AnHarvardNorth Carolina A13210
Matt SchiavoneNorthwesternUC Berkeley B13210
Foster HughesMinnesotaBritish Columbia13310
Tony ChenToronto AColumbia B13310
Ezra SantosChicago BVirginia1330
Tiffany ZhouFloridaIndiana1330
Cade ReinbergerRITNYU1330
Maximilian NieburJohns HopkinsOhio State1330
June YinWUSTL BMichigan13310
Ryan RosenbergNYURIT13310
Teigue KellyPenn StateToronto C1330
Rohan ShelkeUC Berkeley AGeorgia Tech13310
Amogh KulkarniGeorgia StateUCF1330
Soren HeydariNorth Carolina BWaterloo B1330
Adam FineChicago AWinona State1330
Julian BushlowCornell BIllinois B1330
Conor ThompsonIowa StateYale13310
Jason ZhangToronto CPenn State1330