sequence alignment - 2024 PLAYTIME

Question

BLOSUM62 and PAM250 are substitution matrices used for this task. For 10 points each:

[10h] Name this task done by reducing “linear” or “affine” gap penalties using programs such as Clustal. The E-value and bit score of an algorithm for this task are measured by the Karlin–Altschul statistics.

ANSWER: sequence alignment

[10m] This algorithm finds similar sequences through seeding and extends matches into high-scoring segment pair regions until a “dropoff” is reached. It improves on the sequence alignment methods used in FASTA.

ANSWER: BLAST [or Basic Local Alignment Search Tool]

[10e] BLAST can be used for free online on the website for the NCBI, which is a branch of this non-CDC government agency centered in Bethesda that funds biomedical research.

ANSWER: NIH [or National Institute(s) of Health; accept National Library of Medicine or NLM; prompt on HHS or Department of Health and Human Services]

<KP, Biology>

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Summary


2025 PLAYTIME @ CWRU	12/10/2024	Y	4	17.50	100%	75%	0%
2025 PLAYTIME @ Claremont	12/10/2024	Y	5	18.00	100%	60%	20%
2025 PLAYTIME @ Florida	12/10/2024	Y	3	16.67	100%	67%	0%
2024 PLAYTIME @ Harvard	04/26/2025	Y	4	17.50	75%	75%	25%
2024 PLAYTIME @ JHU	10/26/2024	Y	5	8.00	60%	20%	0%
2025 PLAYTIME @ Northwest	12/10/2024	Y	1	30.00	100%	100%	100%
2025 PLAYTIME Online	04/26/2025	Y	9	20.00	100%	78%	22%
2025 PLAYTIME @ Sheffield	12/10/2024	Y	4	7.50	50%	25%	0%
2024 PLAYTIME @ UBC	10/05/2024	Y	7	10.00	57%	29%	14%
2024 PLAYTIME @ Virginia Tech	07/11/2025	Y	3	16.67	100%	67%	0%
2024 PLAYTIME @ WashU	10/12/2024	Y	6	16.67	83%	67%	17%

Data


Michigan B	Ohio State C	0	10	10	20
Art of Premature Signaling	girl 15 whale i mean they	0	10	10	20
Claremont B	Jason B	0	10	10	20
UCLA A	Caltech	0	0	10	10
UCSB	UCLA B	0	0	10	10
Claremont A	UCSD	10	10	10	30
Billy's Bastion	Qin Shi Huang's Immortality Poison	0	10	10	20
Too much from you lately	Edwin Laundrorat's Long-Lost Man Unclothès Rat Degrosses	0	10	10	20
Project2025BC: Make Assyria Great Again	Keeping Up With the Cardassians	0	0	10	10
Lexington	Brandeis	0	0	0	0
Brown	Harvard	0	10	10	20
MIT	Belmont	10	10	10	30
RIT	Boston University	0	10	10	20
Maryland A	George Mason B	0	10	10	20
CWRU	George Mason C	0	0	10	10
NYU B	Georgetown	0	0	0	0
Johns Hopkins A	NYU C	0	0	10	10
Haverford A	Maryland B	0	0	0	0
Alberta	Arizona State University A	10	10	10	30
2 Italians, 2 Poles, All Noles	Quatumvirate	0	0	10	10
Egypt Airlines Haters	Four Generalists in Search of a Power	10	10	10	30
Notre Dame + Epic Games	Free Agents 1	0	10	10	20
Auburn 2026	Goober Gang	0	0	10	10
Illinois Orange	MSJ	0	10	10	20
Mahjonng Masters	mongeese	0	10	10	20
evil women enjoyers	Mike Dukakis Tank Battalion	0	10	10	20
Monsieur Hulot's Academic Team	Gruh	10	10	10	30
we need new names	Trip-Hop Quizzer Tricky	0	10	10	20
Ohio State B	Michigan A	0	0	10	10
Ohio State D	Pittsburgh	0	10	10	20
Ohio State A	Michigan D	0	10	10	20
Birmingham	Sheffield C	0	0	0	0
LSE	Lancaster	0	0	10	10
Manchester	Sheffield A	0	10	10	20
Warwick A	Sheffield B	0	0	0	0
Mac A	UBC	0	0	10	10
McGill A	Toronto C	0	0	0	0
McGill B	Ottawa A	0	0	0	0
Waterloo A	Simon Fraser	0	10	10	20
Toronto A	Toronto B	10	10	10	30
Toronto Metropolitan	Waterloo B	0	0	0	0
Toronto E	Waterloo C	0	0	10	10
4 quizbowl pros go Virginia on North Carolina	Master and Margaritaville	0	10	10	20
Adrianne Lenker 4 Nobel Lit Prize 2K65	Somehow Paula Deen Returned	0	10	10	20
Ashurbanipal’s Drag Race	Even in Blacksburg There I Am	0	0	10	10
Illinois A	Truman State	0	0	10	10
Iowa State	Illinois B	0	10	10	20
Chicago B	WashU Bulbasaur	10	10	10	30
Chicago B	WashU Bulbasaur	10	10	10	30
Chicago B	Missouri	0	10	10	20
Chicago B	Missouri	0	10	10	20
Chicago B	WashU Bulbasaur	10	10	10	30
Chicago B	WashU Bulbasaur	10	10	10	30
Chicago B	Missouri	0	10	10	20
Chicago B	Missouri	0	10	10	20
SIUE	WashU Bulbasaur	0	10	0	10
Chicago A	WashU Squirtle	0	0	10	10