Plcz1-null (“P-L-C-Z-one-null”) mice are characteristically susceptible to this process. Jaffe et al. showed that insufficient sodium ions in water could induce this process in L. variegatus and S. purpuratus. To avoid this process, rendezvin proteins self-assemble, and the membrane protein Juno is rapidly shed to prevent binding with Izumo1. (15[1]-5[1])To inhibit this process, (-5[1])the bindin receptor is cleaved and peroxidase-mediated tyrosine crosslinks (15[1])are formed to strengthen the external (*) vitelline envelope. (-5[1])In mammals, (10[1])ZP (-5[1])glycoproteins are removed by an N-acetyl-glucosaminidase to prevent this process, which is also the purpose of a roughly one-minute positive shift (-5[1])in membrane potential. (-5[1])When this process evades those “fast-block” and cortical granule-based “slow-block” mechanisms, a triploid nucleus is formed. For 10 points, (10[1])name this undesirable biological process in which multiple (-5[1])male gametes fuse with the same egg. ■END■ (10[1]0[13])