Napoleone Ferrara’s lab at this company discovered both the tumor growth factor VEGF (“vej-F”) and its inhibitor Avastin. For 10 points each:
[10h] Name this Silicon Valley biotech company founded by Herb Boyer, who pioneered using recombinant DNA to express eukaryotic proteins in bacteria.
ANSWER: Genentech [or Genentech, Inc.]
[10e] Genentech’s first flagship product was an rDNA-based way of producing this hormone, which they licensed to Eli Lilly. This hormone, which until then had been harvested from pig pancreases, promotes blood glucose absorption.
ANSWER: insulin
[10m] The case Diamond v. Chakrabarty helped the biotech industry grow by legalizing a patent on a recombinant, oil-remediating strain of this genus. This genus’s highly-antibiotic resistant aeruginosa species causes many hospital-acquired infections.
ANSWER: Pseudomonas [accept Pseudomonas aeruginosa; accept Pseudomonas putida; prompt on P. aeruginosa or P. putida]
<VD, Biology>