Question
PSD4/RPN-10 binds to this protein by expressing the LALAL (“L-A-L-A-L”) motif. This protein’s activity can be promoted by incorporating the DCAF (“decaf”) receptor into a “molecular glue” for recruitment of the CUL4-DDB1 (“cull-four D-D-B-one”) complex. This protein’s ability to bind to a substrate is enhanced by a complex composed of Skp1, Cullin, and F-box subunits. Proximity-promoted addition of this protein to other molecules can be facilitated by PROTACs. About 4 monomers of protein must be attached by lysine linkages before its primary function is carried out. A series of 3 ligases add this protein to other proteins to mark them for degradation in the 26S proteasome. For 10 points, name this 76-amino acid “molecular kiss of death” whose name derives from its expression in nearly all eukaryotic cells. ■END■
Summary
2024 ACF Regionals @ Berkeley | 01/27/2024 | Y | 3 | 100% | 0% | 0% | 81.33 |
2024 ACF Regionals @ Cornell | 01/27/2024 | Y | 2 | 100% | 0% | 0% | 123.00 |
2024 ACF Regionals @ JMU | 01/27/2024 | Y | 8 | 75% | 0% | 13% | 106.17 |
2024 ACF Regionals @ Nebraska | 01/27/2024 | Y | 6 | 100% | 0% | 0% | 98.50 |
2024 ACF Regionals @ Ohio State | 01/27/2024 | Y | 3 | 100% | 0% | 0% | 94.33 |
2024 ACF Regionals @ Rutgers | 01/27/2024 | Y | 5 | 80% | 0% | 40% | 82.25 |
2024 ACF Regionals @ Imperial | 01/27/2024 | Y | 8 | 100% | 0% | 0% | 83.75 |
2024 ACF Regionals @ Vanderbilt | 01/27/2024 | Y | 4 | 100% | 0% | 0% | 104.50 |
Buzzes
Player | Team | Opponent | Buzz Position | Value |
---|---|---|---|---|
Oscar Despard | Cambridge A | Cambridge B | 29 | 10 |
Enoch Yuen | Imperial A | Edinburgh | 46 | 10 |
Vishal Kanigcherla (UG) | Penn | NYU B | 49 | -5 |
David Bass | Johns Hopkins | Columbia C | 50 | 10 |
Saketh Dontaraju (DII) | NYU A | Haverford | 50 | -5 |
Allan Lee | Stanford C | Berkeley B | 55 | 10 |
Geoffrey Wu (UG) | Columbia A | Rowan | 55 | 10 |
Ted Warner | Bristol | Kiel | 57 | 10 |
Alexander Harmata | Michigan A | Ohio State A | 64 | 10 |
Sam Moore | Durham A | Imperial B | 65 | 10 |
Rasheeq Azad (UG) | UNC B (UG) | Duke A (UG) | 73 | 10 |
Russell Nip | UBC A | Claremont A | 79 | 10 |
Ryan Humphrey | Texas A | Sorbonne | 86 | 10 |
Munir Siddiqui (UG) | Maryland B (UG) | UNC A (Grad) | 87 | 10 |
Vinu Harihar | Berkeley C | Berkeley A | 92 | 10 |
Iris Pardue (UG) | Kenyon | Cedarville | 95 | 10 |
Natan Holtzman | Stanford B | Stanford A | 97 | 10 |
Amogh Kulkarni | Geodesic | Kentucky | 97 | 10 |
Zander Werner (DII) | Virginia C (UG) | William & Mary A (UG) | 99 | -5 |
Rohan Dalal | Georgia Tech B | Georgia Tech A | 99 | 10 |
Aswath Karai | Michigan State A | Appalachian State | 100 | 10 |
Sam Macchi (DII) | Vassar | John Jay | 100 | 10 |
Bryanna Shao | Vanderbilt A | Alabama | 100 | 10 |
Deepak Muthyala | Texas A&M A | Iowa B | 101 | 10 |
Dimitris Kalafatis | Texas A&M B | UW A | 101 | 10 |
Jacob Robertson | Oxford A | Warwick | 104 | 10 |
Vedang Singhal (DII) | UNC D (DII) | Virginia B (UG) | 110 | 10 |
Kenny Zhang (UG) | Virginia A (UG) | GWU B (Grad) | 121 | 10 |
Alexander Baker | Oxford B | Durham B | 121 | 10 |
Yared Tadesse | Cornell A | Cornell B | 122 | 10 |
Isaac Mammel (UG) | Maryland A (Grad) | JMU B (UG) | 122 | 10 |
Jack Oberman | South Carolina | Harding | 122 | 10 |
Cade Reinberger | RIT B | Binghamton | 124 | 10 |
Michael Eng (UG) | UNC C (UG) | Liberty B (DII) | 124 | 0 |
Andrew Amygdalos (UG) | GWU A (UG) | Maryland C (DII) | 124 | 0 |
Brian Dudley (UG) | William & Mary A (UG) | Virginia C (UG) | 124 | 10 |
Kathy Liang | Rice A | Iowa A | 124 | 10 |
Mitchell Indek | Michigan C | Michigan B | 124 | 10 |
Dennis Yang (DII) | Michigan B | Michigan C | 124 | 0 |
Arjun Bothra (UG) | Haverford | NYU A | 124 | 10 |
Andrew Fisher | Sheffield | KCL | 124 | 10 |
Linus Luu | Cambridge C | Oxford C | 124 | 10 |