Question

SCENIC and CellOracle are methods used to screen perturbations of these proteins in vitro. The HOMER database uses position weight matrices to determine how consistently one of these proteins will bind to its given substrate. (10[1])A class of these proteins that interact with inaccessible regions of their targets are called “pioneers.” The helix-loop-helix (-5[1])domain is a common characteristic (10[1])of these (10[1])proteins, which can be pulled down by antibodies along with their substrate during ChIP. (-5[1])Six of these proteins (-5[1])fold together (10[1])to form the pre-initiation complex. Similarity to the consensus sequence of these proteins determines the strength of genetic enhancers and promoters. For 10 points, name these DNA-binding proteins (-5[1])that (10[1])impact recruitment (-5[1])of RNA polymerase to regulate (10[1])the synthesis of mRNA. (-5[1]) (10[4]0[12])■END■

ANSWER: transcription factors [or TFs; accept DNA-binding proteins until read; prompt on pioneer factors]
<Biology>
= Average correct buzz position

Summary

2024 ACF Regionals @ Berkeley01/27/2024Y3100%0%33%70.33
2024 ACF Regionals @ Cornell01/27/2024Y250%0%50%120.00
2024 ACF Regionals @ JMU01/27/2024Y933%0%33%118.33
2024 ACF Regionals @ Minnesota01/27/2024Y1100%0%0%59.00
2024 ACF Regionals @ Nebraska01/27/2024Y1100%0%0%108.00
2024 ACF Regionals @ Rutgers01/27/2024Y250%0%50%79.00

Buzzes

PlayerTeamOpponentBuzz PositionValue
Vinu HariharBerkeley CStanford C3410
Swapnil GargBerkeley AStanford A52-5
Rohan ShelkeBerkeley BStanford B5710
Bryan UgazArizona StateIowa State5910
Arjun Bothra (UG)HaverfordVassar73-5
Ivvone Zhou (UG)UNC B (UG)Virginia A (UG)77-5
Moses KitakuleColumbia ANYU A7910
Vedang Singhal (DII)UNC D (DII)Duke A (UG)107-5
Kevin ParkClaremont ATexas A10810
Yared TadesseCornell ARIT B110-5
Jacob Martin (UG)Maryland B (UG)Maryland C (DII)11510
Brian Dudley (UG)William & Mary A (UG)Virginia B (UG)119-5
Michał GerasimiukStanford ABerkeley A12010
Cade ReinbergerRIT BCornell A1200
Jacky XuCornell BRIT A12010
Will HooverRIT ACornell B1200
Zander Werner (DII)Virginia C (UG)GWU B (Grad)1200
Logan Mitchell (UG)JMU B (UG)Liberty C (DII)1200
Caleb Kendrick (Grad)Maryland A (Grad)UNC C (UG)12010
Perry O'Connor (Grad)Liberty A (Grad)UNC A (Grad)1200
Joshua Schmidt (DII)Liberty B (DII)GWU A (UG)1200
Nathan Redford (DII)Liberty C (DII)JMU B (UG)1200
Andrew Amygdalos (UG)GWU A (UG)Liberty B (DII)1200
Kenny Zhang (UG)Virginia A (UG)UNC B (UG)1200
Jim Fan (Grad)UNC A (Grad)Liberty A (Grad)1200
Samuel Kassover (DII)GWU B (Grad)Virginia C (UG)1200
Ethan Rehder (UG)Duke A (UG)UNC D (DII)12010
Sam Macchi (DII)VassarHaverford1200