To treat malaria, hydroxychloroquine (“hydroxy-CLORE-oh-quin”) accumulates at these cellular structures and blocks their activity. Organelles named for being “related” to these structures include melanosomes, vacuoles, and other vesicles containing proton pumps. Endocytic vesicles eventually fuse with these structures at the end of a pathway that recycles transmembrane receptors. At the trans-Golgi, any phosphatases, lipases (“LIE-pazes”), or proteases that are tagged with (*) mannose-6-phosphate are (10[1])trafficked (10[1])into these structures. Large vesicles containing defective proteins are absorbed by these structures during autophagy (“uh-TAW-fuh-jee”). The hydrolytic enzymes in these structures must tolerate pHs below 5 while they digest proteins and lipids. For 10 points, name these cellular suicide sacs. ■END■