Question

To treat malaria, hydroxychloroquine (“hydroxy-CLORE-oh-quin”) accumulates at these cellular structures and blocks their activity. Organelles named for being “related” to these structures include melanosomes, vacuoles, and other vesicles containing proton pumps. Endocytic vesicles eventually fuse with these structures at the end of a pathway that recycles transmembrane receptors. At the trans-Golgi, any phosphatases, lipases (“LIE-pazes”), or proteases that are tagged with (*) mannose-6-phosphate are (10[1])trafficked (10[1])into these structures. Large vesicles containing defective proteins are absorbed by these structures during autophagy (“uh-TAW-fuh-jee”). The hydrolytic enzymes in these structures must tolerate pHs below 5 while they digest proteins and lipids. For 10 points, name these cellular suicide sacs. ■END■

ANSWER: lysosomes [prompt on endosomes; prompt on vesicles]
<Adam Silverman, Science - Biology&gt; ~25336~ &lt;Editor: Adam Silverman>
= Average correct buzz position

Buzzes

PlayerTeamOpponentBuzz PositionValue
Arthur GaydenDetroit Country DayRichard Montgomery6010
Jacob BartaDetroit Catholic Central ADallas County6110

Summary

2023 PACE NSC06/10/2023Y2100%0%0%60.50