Question
In 2019, Li et al. devised a 4-mer·capto·pyridine/gold nanostar probe to accurately monitor this quantity via plasmon-enhanced Raman spectroscopy. Phosphorylation of the TFEB gene increases the transcription of a 14-subunit complex crucial to lowering this quantity. Hydroxychloroquine’s anti-autoimmune effect in treating lupus is in part due to its ability to raise this quantity in APCs. Studies that demonstrate poly·ethyl·en·imine’s ability to stabilize this quantity support its role as a (*) “sponge.” Most cathepsins only function within a narrow range of this quantity. Dysfunction of the V-type ATPase that regulates this quantity leads to its increase, which in turn inhibits the function of previously mannose-6-phosphate-tagged hydrolases. For 10 points, what quantity’s normal value of 4 to 5 activates the proteolytic enzymes of a specific organelle? ■END■
Buzzes
Player | Team | Opponent | Buzz Position | Value |
---|---|---|---|---|
Andrew Wang | The anti-STOON-dahl cabal (the tall Keyal et al.) | Team Name Think Detail | 36 | 15 |
Eric Mukherjee | Curse you, Periplus the Platypus! | The Plague (anime)" was redirected to: "Oran High School Host Club | 37 | 15 |
Billy Busse | BHSU | The Catastrophic Implosion of Packet Sub | 64 | -5 |
Shahar Schwartz | Saint Peter Andre 3000 | Romanos IV Diogenes’ Macaroni Grill | 113 | 10 |
Adam Fine | The Catastrophic Implosion of Packet Sub | BHSU | 122 | 10 |