A drug most commonly used to treat this disease is associated with DRESS syndrome in patients with the HLA-B*58:01 (“H-L-A-B-fifty-eight-oh-one”) allele. Calcification of knee cartilage is often observed in a “pseudo” form of this disease called CPPD. Both Lesch–Nyhan syndrome and this disease are treated using febuxostat, allopurinol, and other xanthine oxidase inhibitors. People with this disease sometimes have deposits called tophi on their elbows. A purine-rich diet can worsen this disease, which is diagnosed by finding needle-shaped negatively birefringent crystals in synovial fluid. This disease commonly manifests as podagra, or swelling of the big toe. For 10 points, name this form of inflammatory arthritis in which uric acid crystals deposit in joints, often called the “disease of kings.” ■END■
ANSWER: gout [or arthritis uratica; accept gouty arthritis; accept pseudogout; prompt on hyperuricemia or arthritis]
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= Average correct buzz position