Question

Some members of this genus produce a conformationally-restricted glutamate analogue useful for reversible brain lesioning; a potent GABA-A (“GAB-uh A”) agonist derived from members of this genus has similar applications. A compound named for being discovered in this genus locks RNAPII’s (“R-N-A-P-two’s”) bridge helix into place, halting DNA translocation. Phallotoxins from this genus (10[1])conjugated to rhodamine (10[1])or eosin can be used to visualize muscle fibers because they specifically bind and stabilize F-actin. A species of this genus names a compound that acts as an agonist for a class of namesake G-protein-coupled (10[1])acetylcholine receptors. (-5[1])Muscimol (-5[2])is responsible for (10[1])the psychoactive effects (10[1])of the most famous mushroom (-5[1])of this (10[1])genus, (10[1])which was (10[1])often used as an entheogen. For 10 points, species muscaria (10[1])and phalloides (10[2])(“fal-LOY-deez”) are members of what fungal genus that contains red-and-white spotted fly agarics and toxic (-5[1])death caps? ■END■ (10[1]0[9])

ANSWER: Amanita [accept specific species like Amanita muscaria or Amanita phalloides; prompt on A. muscaria or A. phalloides or destroying angels by asking “what is the genus name?”; prompt on death caps or fly agarics until each is read by asking “what is the genus name?”; prompt on amatoxins or alpha-amanitin or beta-amanitin by asking “what genus is it named for?”] (The lesioning compounds are the glutamate analogue ibotenic acid and the GABA-A agonist muscimol.)
<Biology>
= Average correct buzz position

Summary

2023 ACF Nationals04/22/2023Y1963%0%26%98.08

Buzzes

PlayerTeamOpponentBuzz PositionValue
Geoffrey ChenCornell ANorth Carolina A4910
Adam FineChicago AMaryland A5210
Julian GatchSouth Carolina AIndiana A8710
Andrew HannaVanderbilt AMinnesota A89-5
John MarvinChicago BImperial A90-5
Joelle SmartRutgers APenn A90-5
June YinWUSTL BMcGill A9310
Jonathan LauJohns Hopkins AIowa State A9610
Sharath NarayanNorthwestern AGeorgia Tech B101-5
Lexi TermanRutgers BYale A10310
David BassVirginia AUC Berkeley A10410
Tracy MirkinFlorida AWUSTL A10610
Hari ParameswaranGeorgia Tech AMichigan A11610
Natan HoltzmanStanford AMinnesota B11810
Ian ChowToronto AYale B11810
Roxanne TangOhio State AUC Berkeley B132-5
Dan NiCornell BClaremont A1350
Kevin ParkClaremont ACornell B1350
Qingyu ZhangFlorida BIllinois A1350
Shardul RaoMinnesota AVanderbilt A1350
Halle FriedmanNYU ABrown A1350
S. A. ShenoyGeorgia Tech BNorthwestern A13510
Jason HongBrown ANYU A1350
Yash MandaviaIllinois AFlorida B1350
Benjamin McAvoy-BickfordPenn ARutgers A1350
Rohan ShelkeUC Berkeley BOhio State A1350