Flux balance analysis assumes that all metabolites inside a cell satisfy this condition. For 10 points each:
[10m] Name this condition that occurs in a chemical reaction network if every accumulation term equals zero. Three distinct examples of this condition can satisfy mass and energy balances inside a CSTR.
ANSWER: steady-state concentrations [or stationary states; accept pseudo-steady states or quasi-steady-state; or SS or PSS or QSS; prompt on descriptive answers like not changing or fixed or static over time; prompt on positive equilibria or equilibrium or pseudoequilibrium]
[10e] Steady-state concentrations are eigenvectors of a matrix that encodes rates along with these values for every reaction in the network. Molarity is exponentiated by these coefficients in the law of mass action.
ANSWER: stoichiometric coefficients [or stoichiometry]
[10h] The trajectory to steady-state for discrete molecules in a network can be computed using this stochastic simulation algorithm, which samples chemical reactions from the distribution of their rates in the master equation.
ANSWER: Gillespie algorithm [or Doob–Gillespie algorithm]
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