Question
Cathepsin D cleaves a category of proteins named for this process, which produces a phosphoprotein that is the most phosphorylated protein in nature. For 10 points each:
[10h] Name or describe this process, whose precursors are synthesized by the liver. The vegetal pole contains the most concentrated product of this process.
ANSWER: vitellogenesis [or egg yolk formation; accept vitellogenin; prompt on egg formation or oogenesis] (The protein in the lead-in is phosvitin.)
[10m] Another cleavage product of vitellogenin is the type D domain of these proteins, which complex with factor VIII in platelets. Weibel–Palade bodies store both this protein and P-selectin.
ANSWER: von Willebrand factor [or vWF]
[10e] These other hormones stimulate the synthesis of vitellogenin. During ovulation, a rise in the level of these hormones triggers the “LH surge.”
ANSWER: estrogens [accept estradiols]
<Zhang, Biology>
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