Question
DNA is tethered through nanopores of alpha-hemolysin in one form of this technique. For 10 points each:
[10e] Name this technique that aims to determine the order of DNA molecules within a given sample.
ANSWER: DNA sequencing [or word forms; accept gene sequencing or genomic sequencing; accept DNA-seq; accept next-generation sequencing; accept nanopore sequencing]
[10h] Sequencing reads are usually stored in this file format frequently used to compress genetic data. A Phred quality score is added onto a variant of this type of file whose name replaces an “A” with a “Q.”
ANSWER: FASTA files [accept FASTQ files]
[10m] The rise of next-generation sequencing has allowed for analysis of these genetic elements via genome-wide association studies. These markers are essentially point mutations that persist in at least 1 percent of the human population.
ANSWER: single nucleotide polymorphisms [or SNPs (“snips”)]
<Biology>